1,4-二氮杂二环[2.2.2]辛烷促进三酮单水合物和活泼炔通过连续碳-碳/碳-氧键断裂的加成反应  

1,4-Diazabicyclo[2.2.2]octane-Promoted Addition Reaction of Tricarbonyl Monohydrates with Active Alkynes via Consecutive C—C/C—O Cleavage

作　　者：张金凤 叶如意 李子阳 孟令国[1] Zhang Jinfeng;Ye Ruyi;Li Ziyang;Meng Lingguo(School of Chemistry and Materials Science,Huaibei Normal University,Huaibei,Anhui 235000)

机构地区：[1]淮北师范大学化学与材料科学学院,安徽淮北235000

出　　处：《有机化学》2021年第11期4384-4390,共7页Chinese Journal of Organic Chemistry

基　　金：安徽高校自然科学研究基金(Nos.KJ2020A0045,KJ2020B01)资助项目.

摘　　要：在无金属和温和反应条件下,发展了新颖的三酮单水合物与活泼炔通过连续碳-碳/碳-氧断裂的加成反应,且反应可高效地在1 min内完成.多样的三酮单水合物均可在1,4-二氮杂二环[2.2.2]辛烷(DABCO)的促进下,通过这种转变与活泼炔反应,生成多种酯类化合物.A novel addition reaction of vicinal tricarbonyl monohydrates with active alkynes proceeded via rapid consecutive C—C/C—O cleavage processes under metal-free and mild reaction conditions,and the transformation was completed within only 1 min.Diverse tricarbonyl monohydrates could react with active alkynes to produce carboxylate esters via these transformations in the presence of 1,4-diazabicyclo[2.2.2]octane(DABCO).

关 键 词：碳-碳键断裂 碳-氧键断裂 加成 促进 

分 类 号：O621.256.7[理学—有机化学]