500例孕晚期妇女阴道或直肠拭子GBS定植率及GBS感染影响因素分析  

Analysis of GBS colonization rate of vagina or rectal swabs and influencing factors of GBS infection in 500 women in the third trimester of pregnancy

作　　者：余蓉 葛玉东 YU Rong;GE Yudong(Department of Laboratory,Xuchang maternal and Child Health Hospital,Xuchang Henan 461700,China)

机构地区：[1]许昌市妇幼保健院检验科,河南许昌461700

出　　处：《临床研究》2021年第12期132-135,共4页Clinical Research

摘　　要：目的500例孕晚期妇女阴道或直肠拭子B族链球菌(GBS)的定植率及GBS感染影响因素分析。方法选取2020年1月至2020年12月许昌市妇幼保健院妇产科的500例孕晚期妇女作为研究对象,对阴道及直肠拭子进行GBS培养,统计GBS定植率;并对阳性标本分离的菌株进行药物敏感性试验,检查感染情况,根据培养结果将研究对象分为GBS阳性组(47例)和GBS阴性组(453例),分析孕晚期妇女阴道或直肠拭子GBS定植率和GBS感染率,并采用多因素Logistic回归分析孕晚期妇女GBS感染率的影响因素。结果GBS在直肠定植率为6.40%,阴道定植率为7.80%,其中,GBS感染阳性率为9.40%,GBS感染阴性率为90.60%;GBS阳性组和GBS阴性组一般资料比较差异均无统计学意义(P>0.05);GBS阳性组年龄>35岁、文化程度为初中及以下、有妊娠期并发症、有阴道炎史、孕前体质量指数≥28kg/m^(2)的占比均较GBS阴性组高,差异均有统计学意义(P<0.05);多因素Logistic回归分析发现,年龄>35岁(OR=6.547,95%CI=2.878~14.893)、文化程度在初中及以下(OR=7.135,95%CI=3.136~16.230)、阴道炎史(OR=7.917,95%CI=3.480~18.009)、妊娠期并发症(OR=8.281,95%CI=3.640~18.383)、孕前体质量指数≥28kg/m^(2)(OR=2.770,95%CI=1.140~6.733)均是孕晚期妇女GBS感染的影响因素(P<0.05)。结论孕晚期妇女GBS定植率较低,年龄、文化程度、阴道炎史、妊娠期并发症是孕晚期妇女GBS感染的影响因素,临床上应根据影响因素对孕晚期妇女采取相应治疗,以提高孕妇生活质量。Objective To analyze the colonization rate and infection factors of group B streptococcus(GBS)from vaginal or rectal swabs of 500 women in the third trimester of pregnancy.Methods From January 2020 to December 2020,500 women in the third trimester of pregnancy in the Department of Obstetrics and Gynecology of Xuchang Maternal and Child Health Hospital were selected as the research objects.Use chromogenic medium to detect vaginal and rectal swabs for GBS culture,and count GBS colonization rate.And conduct drug susceptibility tests on strains isolated from positive specimens to check for infections.Divided into GBS positive group(47 cases)and GBS negative group(453 cases)according to infection results.Analysis of GBS colonization rate and GBS infection rate of vaginal or rectal swabs of women in the third trimester of pregnancy.Multivariate Logistic regression was used to analyze the influencing factors of GBS infection rate in late pregnancy women.Results The colonization rate of GBS in the rectum was 6.40%,and the rate of vaginal colonization was 7.80%.Among them,the positive rate of GBS infection was 9.40%,and the negative rate of GBS infection was 90.60%.There were no statistically significant differences between the two groups in economic conditions,history of miscarriage,parity,history of premature birth,living environment,occupation,height,history of uterine cavity operation,history of smoking,history of drinking,history of urinary tract infection,and ethnicity(P>0.05).The GBS-positive group was older than 35 years old,the education level was junior high school or younger,has pregnancy complications,had a history of vaginitis,and the pre-pregnancy body mass index was greater than or equal to 28kg/m^(2) the proportion of cases weer higher than that of the GBS-negative group(P<0.05).After Logistic regression analysis,age(OR=6.547,95%CI=2.878~14.893),education level(OR=7.135,95%CI=3.136~16.230),history of vaginitis(OR=7.917,95%CI=3.480~18.009),pregnancy complications(OR=8.281,95%CI=3.640~18.383),pre-pregnancy b

关 键 词：孕晚期 B族链球菌 显色培养基 定植率 感染 影响因素 

分 类 号：R446[医药卫生—诊断学]