海水养殖病原弧菌对鱼类宿主定植机制研究进展  

Review on Host-invaded Colonization and Regulatory Mechanism by Pathogenic Vibrio in Mariculture

作　　者：张依琳 吴凡 简纪常[1] 蔡双虎[1] ZHANG Yi-lin;WU Fan;JIAN Ji-chang;CAI Shuang-hu(Fisheries College,Guangdong Ocean University,Guangdong Provincial Key Laboratory of Pathogenic Biology and Epidemiology for Aquatic Economic Animals,Zhanjiang 524088,China)

机构地区：[1]广东海洋大学水产学院,广东省水产经济动物病原生物学及流行病学重点实验室,广东湛江524088

出　　处：《广东海洋大学学报》2021年第6期138-146,共9页Journal of Guangdong Ocean University

基　　金：广东省自然科学基金(2017A030307033);国家自然科学基金(31572656)。

摘　　要：定植是海水病原弧菌侵染宿主并引起弧菌病过程中最重要的环节之一,开展弧菌定植分子机制研究对充分阐明弧菌的致病性从而制定有效防控策略极为重要。从特定结构蛋白、生物膜、调控系统3个方面对海水养殖弧菌病原在鱼类肠道定植机制研究进展进行归纳总结,并提出研究展望,有助于更全面、深入认识海洋病原弧菌对鱼类肠道的定植,对进一步研究病原菌对鱼类肠道定植机制有重要参考价值。Colonization is one of the most important link in the process of Vibrio infecting the host and causing vibriosis in mari-culture.Therefore,it is very important to study the molecular mechanism of Vibrio colonization in order to fully clarify the pathogenicity of Vibrio and develop effective prevention and control strategies.This review summarized the research progress of the molecular mechanism of Vibrio colonization on fish intestine from three aspects of specific structural protein,biofilm and regulatory system,and conclusion can lay a foundation for revealing the internal causes of Vibrio outbreak in mari-culture.This review is conducive to a more comprehensive and in-depth understanding of the colonization of fish intestinal tract by marine pathogenic Vibrio,which has important reference value for further research on the mechanism of the colonization of fish intestine by pathogenic bacteria.

关 键 词：弧菌 定植 生物膜 特定结构蛋白 调控系统 

分 类 号：S941[农业科学—水产养殖]