北京市西城区7382例常见呼吸道病原体IgM抗体检测结果分析  

Analysis of IgM antibody test results against 8 common respiratory pathogens of 7382 patients in Xicheng district of Beijing

作　　者：王晓宁[1] 李卓敏 刘杨 郑芳芳[1] 聂秋燕 刘晴[1] 古媛[1] 韩旭 田野[1] 谭延国[1] WANG Xiaoning;LI Zhuomin;LIU Yang;ZHENG Fangfang;NIE Qiuyan;LIU Qing;GU Yuan;HAN Xu;TIAN Ye;TAN Yanguo(Department of Clinical Laboratory,Fuxing Hospital,Capital Medical University,Beijing 100038,China;Department of Laboratory Medicine,Capital Medical University,Beijing 100038,China)

机构地区：[1]首都医科大学附属复兴医院检验科,北京100038 [2]首都医科大学医学检验系,北京100038

出　　处：《国际检验医学杂志》2021年第24期2949-2952,共4页International Journal of Laboratory Medicine

基　　金：北京市临床重点专科医学检验科培育项目[京卫医(2020)129号]。

摘　　要：目的探讨北京市西城区呼吸道感染患者常见病原体感染的分布情况。方法回顾性分析2016年12月至2019年11月7382例因呼吸道感染就诊的患者资料,采用间接免疫荧光法定性检测血清中常见8种病原体的IgM抗体。结果在7382例患者中,40.92%的患者至少检测出1种病原体IgM抗体;B型流感病毒(INFB)检出率最高,为18.56%;合并感染以A型流感病毒(INFA)+INFB最多。0~<18岁患者以INFB及肺炎支原体(MP)感染最多,INFA及嗜肺军团菌感染好发于18~<40岁年龄组患者,呼吸道合胞病毒(RSV)感染最常见于>65岁患者,肺炎衣原体的检出率随年龄增长呈下降趋势。INFB、INFA及MP感染常见于冬季,其余病毒呈全年散发状态。不同性别间RSV及MP检出率差异有统计学意义(P<0.05)。结论北京市西城区呼吸道病原体检出率以INFB最高,冬季是INFB、INFA及MP感染的高发季节,呼吸道病原体的感染与患者年龄、性别有关。Objective To investigate the epidemiological feature of common pathogens in patients with respiratory tract infection in Xicheng District of Beijing.Methods A retrospective analysis was performed on 7382 patients with respiratory tract infection symptoms from December 2016 to November 2019.IgM antibodies against 8 common pathogens in all of the 7382 patients were tested by indirect immunofluorescence method.Results At least one pathogen IgM antibody was detected in 40.92%of 7382 patients.The detection rate of influenza virus B(INFB)was the highest(18.56%),the co-infection rate of influenza virus A(INFA)and INFB was the highest.INFB and Mycoplasma pneumoniae(MP)were the most common infection pathogens in patients aged 0-<18 years,INFA and Legionella pneumophila infection were most common in patients aged 18-<40 years,and respiratory syncytial virus(RSV)infection was most common in patients aged>65 years.The detection rate of chlamydia pneumoniae decreased with the increase of age.New INFB,INFA and MP infections were common in winter,and other viruses were sporadic throughout the year.The detection rates of RSV and MP were different between different genders(P<0.05).Conclusion INFB detection rate is the highest in Xicheng District of Beijing.Winter is the season with the highest incidence of INFB,INFA and MP infection,and the infection of respiratory pathogens relates to age and gender.

关 键 词：呼吸道感染 呼吸道病原体 IGM抗体 

分 类 号：R446.6[医药卫生—诊断学]