上海地区银屑病患者吸烟、饮酒情况及其与银屑病发病的关联性分析  

The prevalence of tobacco smoke and alcohol drink and its association with the occurrence of psoriasis among psoriasis patients in Shanghai

作　　者：王瑞平 陈思婷 位磊 蒯仂 孙晓颖[2] 李欣[2] 于宁[1] 强燕 李斌[1] WANG Ruiping;CHEN Siting;WEI Lei;KUAI Le;SUN Xiaoying;LI Xin;YU Ning;QIANG Yan;LI Bin(Clinical Research Center,Shanghai Skin Disease Hospital,School of Medicine,Tongji University,Shanghai 200443,China;Department of Dermatology,Yueyang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine,Shanghai 200437,China)

机构地区：[1]上海市皮肤病医院,同济大学附属皮肤病医院皮肤内科临床研究中心,上海200443 [2]上海中医药大学附属岳阳中西医结合医院皮肤科,上海200437

出　　处：《世界临床药物》2021年第11期994-999,共6页World Clinical Drug

基　　金：国家重点研发计划“中医药现代化研究”重点专项(2018YFC1705301);上海申康医院发展中心管理研究项目(2020SKMR-32)。

摘　　要：目的分析银屑病与吸烟、饮酒的关联性,为银屑病患者的健康宣教和后期危险因素干预提供依据。方法采用病例对照研究设计,整合2020年6月至2021年5月银屑病专病门诊数据和“上海慢病人群队列”社区居民调查数据,应用SAS9.4软件进行统计分析。结果720例银屑病患者平均年龄(44.74±11.29)岁,36698名社区居民的平均年龄(56.36±11.29)岁;银屑病患者的吸烟率和现在吸烟率分别为25.83%和22.92%,饮酒率和现在饮酒率分别为16.94%和15.14%。多因素分析显示,银屑病患者吸烟率(OR=3.63,95%CI:2.65~4.99),现在吸烟率(OR=4.77,95%CI:3.38~6.73)明显高于社区居民;饮酒率(OR=1.87,95%CI:1.40~2.52)和现在饮酒率(OR=2.38,95%CI:1.72~3.30)也明显高于社区居民。结论上海地区银屑病患者吸烟率和饮酒率高,吸烟、饮酒与银屑病发病存在关联。建议开展健康宣教,提高银屑病患者对吸烟和饮酒可增加银屑病复发风险和疾病严重程度的认知,帮助患者积极戒烟和戒酒,促进患者身心健康。Objectives To analyze the correlation between psoriasis and smoking,drinking,and provide the basis for health education and risk factors intervention of patients with psoriasis.Methods A case-control study was used to integrate the psoriasis outpatients data from June 2020 to may 2021 and the community survey data from residents of"Shanghai chronic disease population cohort",and SAS 9.4 software was used for statistical analysis.Results The average age of 720 psoriasis patients was(44.74±11.29)and that of 36698 community residents was(56.36±11.29).The prevalence of tobacco smoking and current tobacco smoking in psoriasis patients were 25.83%and 22.92%,and the prevalence of alcohol drinking and current alcohol drinking were 16.94%and 15.14%.Multivariate logistic analysis showed that the smoking prevalence of psoriasis patients(OR=3.63,95%CI:2.65-4.99)was significantly higher than that of community residents(OR=4.77,95%CI:3.38-6.73).The prevalence of drinking(OR=1.87,95%CI:1.40-2.52)and current drinking(OR=2.38,95%CI:1.72-3.30)were also significantly higher than those of community residents.Conclusion The prevalence of smoking and drinking was high in patients with psoriasis in Shanghai,and there was a correlation between smoking and drinking and the incidence of psoriasis.It is suggested that health education should be carried out to improve the awareness of smoking and drinking in patients with psoriasis,which can decrease the risk of recurrence of psoriasis and the severity of the disease,help patients to actively quit smoking and drinking,and promote the physical and mental health of patients.

关 键 词：银屑病 吸烟率 饮酒率 发生率 关联性 

分 类 号：R184[医药卫生—流行病学]