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作 者:陈莉萍[1] 肖文静 吴小刚[1] 管文辉[1] 魏庆[1] 朱银霞[1] 胡海洋[1] 李莉[1] 陈林萍[3] CHEN Li-ping;XIAO Wen-jing;WU Xiao-gang;GUAN Wen-hui;WEI Qing;ZHU Yin-xia;HU Hai-yang;LI Li;CHEN Lin-ping(Department of HIV/STD Prevention and Control,Jiangsu Provincial Center for Disease Control and Prevention,Nanjing,Jiangsu 210009,China)
机构地区:[1]江苏省疾病预防控制中心性病与艾滋病防治所,江苏南京210009 [2]南京医科大学公共卫生学院 [3]南京市中西医结合医院
出 处:《中国预防医学杂志》2021年第6期423-427,共5页Chinese Preventive Medicine
基 金:江苏省卫生健康委科研基金资助项目(Z2018039)。
摘 要:目的了解江苏省疾病预防控制中心艾滋病自愿咨询检测门诊(voluntary counseling and testing,VCT)男男同性性行为人群(men who have sex with men,MSM)人类免疫缺陷病毒(human immunodeficiency virus,HIV)感染趋势及相关影响因素,为评价艾滋病防控效果及制定防治策略提供依据。方法2013—2018年,招募年龄≥16岁,在过去1年与男性发生过肛交或口交性行为,知情同意并自愿参与本调查的MSM,分析HIV感染的影响因素。结果2013—2018年共调查MSM 6976人,HIV感染率、梅毒抗体阳性率和合并感染率均呈上升趋势,差异有统计学意义(P<0.05)。多因素logistic回归分析显示,最近6个月与同性发生无保护肛交性行为(OR=1.58,95%CI:1.31~1.92)、最近6个月与异性发生无保护性行为(OR=0.65,95%CI:0.43~0.81)、最近6个月未接受过艾滋病检测(OR=2.30,95%CI:1.90~2.79)、梅毒感染(OR=2.23,95%CI:1.82~2.74)为HIV感染的影响因素。结论2013—2018年VCT门诊MSM HIV感染呈上升趋势,应加强对该人群的行为干预,加大安全套使用的宣传,制定针对性的艾滋病防治措施。Objective To understand the trend of prevalence of HIV infection among men who have sex with men(MSM)from 2013 to 2018,and to discuss its influencing factors,so as to provide evidence for AIDS prevention and control strategy making.Methods MSM aged≥16 years old,who had anal or oral sex with men in the past year were recruited from voluntary counseling and testing(VCT)clinics of Jiangsu Provincial Center for Disease Control and Prevention from 2013 to 2018 with informed consent.A questionnaire survey was conducted and blood samples were collected for HIV antibody and syphilis antibody detection.The trend chi-square test was used for HIV infection trend analysis and logistics regression model was used to analyze the influencing factors of HIV infection.Results A total of 6976 MSM were recruited from 2013 to 2018.The infection rates of HIV,syphilis and co-infection rate increased from 2013 to 2018,the differences were statistically significant(P<0.05).Multivariate logistic regression analysis showed that having unprotected sex with male partners(OR=1.58,95%CI:1.31-1.92)or with female partners(OR=0.65,95%CI:0.43-0.81)and not having HIV antibody tested(OR=2.30,95%CI:1.90-2.79)in the last 6 months and syphilis infection(OR=2.23,95%CI:1.82-2.74)were the major influencing factors for HIV infection.Conclusions From 2013 to 2018,the prevalence of HIV infection is on the rise among MSM in VCT clinics.Therefore,behavioral intervention should be strengthened and condom use should be encouraged among MSM to prevent HIV infection.
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