免疫球蛋白G4相关性冠状动脉炎的诊断进展  

Progress in the diagnosis of immunoglobulin G4-related coronary arteritis

作　　者：苗来生 戴汝平[3,4,5] Lai-Sheng MIAO;Ru-Ping DAI(School of Medicine,Shanxi Datong University,Datong 037009,Shanxi Province,China;Datong Ruici Medical Imaging Diagnostic Center,Datong 037005,Shanxi Province,China;Chinese Academy of Medical Science&Peking Union Medical College,Beijing 100730,China;National Center for Cardiovascular Diseases,Beijing 102308,China;Department of Radiology,Fuwai Hospital,Chinese Academy of Medical Sciences,Beijing 100037,China)

机构地区：[1]山西大同大学医学院,山西大同037009 [2]大同瑞慈医学影像诊断中心,山西大同037005 [3]中国医学科学院北京协和医学院,北京100730 [4]国家心血管病中心,北京102308 [5]中国医学科学院阜外医院放射影像科,北京100037

出　　处：《医学新知》2021年第6期466-471,共6页New Medicine

摘　　要：免疫球蛋白G4(immunoglobulin G4,IgG4)相关性冠状动脉炎的组织病理学特点是冠状动脉外膜的组织中有大量IgG4阳性浆细胞浸润,引起外膜纤维化及弥漫性肿大,形成围绕冠状动脉周围的肿块,动脉壁呈瘤样增厚。冠状动脉CT血管成像(coronary artery computed tomography angiography,CCTA)显示冠状动脉管壁增厚及周围瘤样肿块形成的槲寄生征,是本病的特征性表现之一,也是诊断的重要依据。本文围绕IgG4相关性冠状动脉炎的病理、影像学特征及诊断标准作一综述。The histopathological features of IgG4-related coronary arteritis involve a large number of IgG4-positive plasma cell infiltrates in the tissues of the coronary adventitia,causing adventitia fibrosis and diffuse enlargement,forming a boudoir mass around the coronary artery with neoplastic thickening of the artery wall.CT angiography of the coronary artery shows the thickening of the coronary vessel wall and the mistletoe sign formed by the surrounding tumor-like mass which are the characteristic manifestations of this disease.This article expounds on IgG4-related coronary arteritis and explains its pathogenesis,imaging features and diagnostic criteria.

关 键 词：免疫球蛋白G4 冠状动脉炎 诊断标准 槲寄生征 

分 类 号：R543.3[医药卫生—心血管疾病]