Electrochemical Dimethyl Sulfide-Mediated Esterification of Amino Acids  

作　　者：Yongli Li Huamin Wang Heng Zhang Aiwen Lei 

机构地区：[1]College of Chemistry and Molecular Sciences,The Institute for Advanced Studies(IAS),Wuhan University,Wuhan,Hubei,430072 China [2]National Research Center for Carbohydrate Synthesis,Jiangxi Normal University,Nanchang,Jiangxi,330022 China

出　　处：《Chinese Journal of Chemistry》2021年第11期3023-3028,共6页中国化学（英文版）

基　　金：This work was supported by the National Natural Science Foundation of China(No.22031008)and the Science Foundation of Wuhan(No.2020010601012192);The Program of Introducing Talents of Discipline to Universities of China(111 Program)is also appreciated;This work was dedicated to Professor Christian Bru-neau for his outstanding contribution to catalysis.

摘　　要：Dimethyl sulfide-mediated electrochemical synthetic strategy for esterification of amino acids has been reported.A series of amino acids could react smoothly with alcohols,affording the desired esterification products with good efficiency.Importantly,the tolerance of peptides and gram-scale synthesis shed light on the utility of this protocol.Mechanistically,the dimethyl sulfide as a mediator plays an essential role in the transformation of amino acids.

关 键 词：ELECTROCHEMISTRY Amino acids Dimethyl sulfide OXIDATION Gram scale synthesis 

分 类 号：O62[理学—有机化学]