脂肪乳剂在新生儿肠外营养治疗中的研究进展  

Research progress on lipid emulsion in neonatal parenteral nutrition

作　　者：吴洁[1] 王欣[1] WU Jie;WANG Xin(Department of Pharmacy,Lu'an People's Hospital Affiliated to Anhui Medical University,Anhui Lu'an 237000,China)

机构地区：[1]安徽医科大学附属六安市人民医院药学部,安徽六安237000

出　　处：《临床药物治疗杂志》2021年第11期1-5,共5页Clinical Medication Journal

基　　金：六安市人民医院2021年度新技术新项目(2021xjs33)。

摘　　要：肠外营养(PN)被广泛应用于早产儿,是预防营养缺乏相对安全的手段。欧洲儿科胃肠病学、肝病学和营养协会、欧洲肠外肠内营养学会、欧洲儿科研究学会和中国肠外肠内营养学会在关于儿童PN的最新指南中均指出,静脉注射用脂肪乳剂(IVLE)是新生儿PN中不可或缺的组成部分。本研究通过回顾IVLE的发展,以及检索近年来使用营养支持的新生儿临床试验研究,分析了PN中不同类型脂肪乳剂的使用情况,以评估不同脂肪乳剂的选择对新生儿患者临床结局可能带来的不同影响。Parenteral nutrition(PN)has been widely used in preterm infants and it is a relatively safe method to prevent nutritional deficiencies. European Pediatric Gastroenterology,Hepatology and Nutrition Association,European Society for Parenteral and Enteral Nutrition,European Society for Pediatric Research and Chinese Society for Parenteral and Enteral Nutrition all pointed out in the latest guidelines on PN for children that intravenous lipid emulsion(IVLE)is an indispensable part of neonatal PN. This article reviewed the development of IVLE and research trials of preterm infants using nutritional support in recent years to investigate the use of various lipid emulsions in PN,and to evaluate the different lipid emulsions may have different effects on the clinical outcomes of neonatal patients.

关 键 词：脂肪乳剂 新生儿 早产儿 肠外营养 

分 类 号：R977.6[医药卫生—药品]