超声引导下微波消融治疗甲状腺良性结节34例近期评估  

Short term evaluation of ultrasound-guided microwave ablation in the treatment of 34 cases of benign thyroid nodules

作　　者：李保启[1] 王佳佳[1] 王金萍[1] 周维风 伍宏兵[1] LI Baoqi;WANG Jiajia;WANG Jinping;ZHOU Weifeng;WU Hongbin(Department of Ultrasound Medicine,The First Affiliated Hospital of Anhui Traditional Chinese Medical University,Hefei,Anhui 230031,China)

机构地区：[1]安徽中医药大学第一附属医院超声医学科,安徽合肥230031

出　　处：《安徽医药》2022年第1期66-69,共4页Anhui Medical and Pharmaceutical Journal

摘　　要：目的探讨超声引导下微波消融治疗甲状腺良性结节的安全性及近期有效性。方法选取2017年7月至2019年6月在安徽中医药大学第一附属医院就诊的34例甲状腺良性结节病人,排除禁忌证均接受超声引导下微波消融治疗,观察记录围手术期并发症及不良反应,术后1、3、6个月随访甲状腺结节的体积缩小率(volume-reduction ratio,VRR)。结果34例病人均无严重的并发症。本研究43枚结节均顺利完成微波消融治疗,一次性消融率为100%。实性结节术前体积(12.13±16.35)mL,术后1个月、3个月、6个月体积为(10.85±15.52)mL、(7.56±12.10)mL、(4.96±9.20)mL,VRR为(14.29±5.51)%、(49.65±12.12)%、(77.18±15.38)%;囊实性结节术前体积为(11.76±14.43)mL,术后1个月、3个月、6个月体积为(9.01±11.02)mL、(5.14±6.82)mL、(2.04±2.78)mL,VRR为(22.88±8.73)%、(56.85±8.74)%、(85.31±6.62)%;实性结节、囊实性结节微波消融术后1个月、3个月、6个月结节的体积均进行性缩小,术后1个月、3个月、6个月结节的VRR相比均差异有统计学意义(P<0.05)。两组结节微波消融术后不同时间随访结节VRR比较,术后1个月、3个月囊实性结节明显优于实性结节VRR(P<0.05),而术后6个月,两组间差异无统计学意义(P=0.102)。结论超声引导下微波消融治疗甲状腺良性结节具有并发症少、疗效显著的特点,是一种安全、有效、值得临床推广的方法。Objective To investigate the safety and short-term effectiveness of ultrasound-guided microwave ablation in the treatment of benign thyroid nodules.Methods Thirty-four patients with benign thyroid nodules who were treated in the First Affiliated Hospital of Anhui Traditional Chinese Medical University from July 2017 to June 2019 were selected.After exclusion of contraindications,all patients received ultrasound-guided microwave ablation.Perioperative complications and adverse reactions were observed and recorded.Volume-reduction ratio(VRR)of thyroid nodules was followed up 1,3 and 6 months after operation.Results There were no serious complications in 34 patients.In this study,43 nodules were successfully treated by microwave ablation,and the ablation rate was 100%.The volume of solid nodules before operation was(12.13±16.35)mL,and the volume at 1 month,3 months and 6 months after operation were(10.85±15.52)mL,(7.56±12.10)mL and(4.96±9.20)mL,respectively.The volume reduction rates were(14.29±5.51)%,(49.65±12.12)%and(77.18±15.38)%,respectively.The volume of cystic and solid nodules before operation was(11.76±14.43)mL.The volume at 1 month,3 months and 6 months after operation was(9.01±11.02)mL,(5.14±6.82)mL and(2.04±2.78)mL,respectively.The volume reduction rates were(22.88±8.73)%,(56.85±8.74)%and(85.31±6.62)%,respectively.After microwave ablation of solid and cystic solid nodules,the volume of nodules decreased gradually at 1,3 and 6 months,and the VRR of nodules at 1,3 and 6 months after microwave ablation was statistically significant(P<0.05).Compared with VRR of the two groups at different time after microwave ablation,the cystic solid nodule was significantly better than the solid nodule at 1 and 3 months postoperatively,and the difference between the two groups was statistically significant(P<0.05),but there was no significant difference between the two groups at 6 months(P=0.102).Conclusion Ultrasound guided microwave ablation for benign thyroid nodules is characterized by less complications a

关 键 词：甲状腺结节 微波消融 超声外科手术 安全性 有效性 

分 类 号：R653[医药卫生—外科学]