含催化单元的单层保护纳米Au水解酶的研究进展  

Development of monolayer-protected gold clusters-based hydrolytic nanozymes containing catalytic units

作　　者：李芳[1] 李帅冰 姚美霞 沈江珊[1] Fang Li;Shuaibing Li;Meixia Yao;Jiangshan Shen(College of Materials Science and Engineering,Huaqiao University,Xiamen 361021,China)

机构地区：[1]华侨大学材料科学与工程学院,厦门361021

出　　处：《中国科学：化学》2021年第12期1579-1589,共11页SCIENTIA SINICA Chimica

基　　金：福建省引导性项目(编号:2020Y0038);厦门市科技局项目(编号:3502Z20193029)资助。

摘　　要：纳米酶能够在生理条件下催化天然酶所介导的生化反应,表现出天然酶所具有的反应动力学过程和催化机制.在单层保护纳米Au (Au MPCs)表面自组装催化单元可大大提高纳米酶的催化能力,近年来发展迅速.本文总结了近年来含催化单元的Au MPCs水解酶的研究进展,重点讨论了Au MPCs水解酶表层催化单元的设计、超分子组装及其应用.Nanozymes can catalyze the biochemical reactions mediated by natural enzymes under physiological conditions, and show natural enzymes-like reaction kinetics and catalytic mechanism. Monolayer-protected gold clusters(Au MPCs) containing catalytic units can greatly improve the catalytic abilitys of nanozymes, so it has been developed rapidly in recent years. In this review, the progress of Au MPCs hydrolytic nanozymes containing catalytic units in recent years is summarized. The design of surface catalytic units, supramolecular assembly and application of Au MPCs hydrolytic nanozymes are discussed.

关 键 词：Au MPCs 催化反应 人工水解酶 

分 类 号：TQ426.97[化学工程] TB383.1[一般工业技术—材料科学与工程] Q814[生物学—生物工程]