天然产物抗动物螨病研究进展  

Advancement of natural products against animal acariasis

作　　者：尚小飞[1] 代立霞 潘虎[1] 苗小楼[1] 张继瑜[1] SHANG Xiaofei;DAI Lixia;PAN Hu;MIAO Xiaolou;ZHANG Jiyu(Key Lab of New Animal Drug Project,Gansu Province,Key Lab of Veterinary Pharmaceutics Development,Ministry of Agriculture and Rural Affairs,Lanzhou Institute of Husbandry and Pharmaceutical Science of CAAS,Lanzhou Gansu 730050,China)

机构地区：[1]中国农业科学院兰州畜牧与兽药研究所农业农村部兽用药物创制重点实验室甘肃省新兽药工程重点实验室,甘肃兰州730050

出　　处：《中兽医医药杂志》2021年第6期32-36,共5页Journal of Traditional Chinese Veterinary Medicine

基　　金：国家自然科学基金面上项目(31772790);中国农业科学院基本科研业务费项目(Y2019XK14,1610032021005)。

摘　　要：动物螨病是动物主要的外寄生虫疾病之一,严重影响动物健康和畜牧业发展,带来一定的经济损失。目前,天然产物已成为新兽药研制的重要来源,天然产物杀螨剂的研发已成为研究热点。通过对近年天然产物抗动物螨病的研究成果和相关文献进行综述,以期发现具有良好研发前景的天然产物。研究发现,部分挥发油、生物碱、苯丙素类、醌类和其他类天然产物均具有一定的杀螨活性,其中,丁香油、6-甲氧基二氢血根碱、丁香酚、4-甲氧基香豆素、胡桃醌等杀螨活性较好,可为后续新型杀螨剂的研发提供参考。As one of important veterinary skin diseases,animal acariasis could reduce the productivity and the quality of animal products.In this paper,we reviewed the advancement of natural products against animal acariasis.Results showed that a serials of the active compounds with the acaricidal activity were found,especially for clove oil in the essential oils,6-methoxydihy-drosanguinarine in alkaloids,eugenol and 4-methoxycourmain in penylpropanoids,juglone in quinones.This review provides the information for the development of potential acaricidal agents.However,the researches lack of depth and width,and should be payed more attention.

关 键 词：螨虫 天然产物 挥发油 苯丙素类 综述 

分 类 号：S855.9[农业科学—临床兽医学]