不同病因产前发热的临床特征与鉴别及宫内感染性产前发热对妊娠结局的影响  

Clinical characteristics and differentiation of different causes of prenatal fever and the influence of intrauterine infectious prenatal fever on pregnancy outcome

作　　者：吴丽侠 刘素彬 高静 贾玉玲 李海英[1] 剧亚茹 段丽红[1] 方芳[1] WU Li-xia;LIU Su-bin;GAO Jing(Department of Obstetrics,Shijiazhuang Fourth Hospital(Obstetrics and Gynecology Hospital Affiliated to Hebei Medical University),Shijiazhuang Hebei 050000,China)

机构地区：[1]石家庄市第四医院(河北医科大学附属妇产医院)产科,河北石家庄050000

出　　处：《临床和实验医学杂志》2021年第24期2648-2651,共4页Journal of Clinical and Experimental Medicine

基　　金：河北省医学科学研究重点课题计划目录项目(编号:20191433)。

摘　　要：目的探讨不同病因产前发热的临床特征与鉴别及宫内感染性产前发热对妊娠结局的影响。方法回顾性选取2018年1月至2021年1月在石家庄市第四医院治疗的产前发热产妇90例作为观察组,同时选取正常妊娠产妇180例作为对照组。分析观察组产前发热病因,比较观察组和对照组,观察组的感染性和非感染性发热产妇的妊娠结局以及新生儿结局差异。Logistic回归分析评估影响产前发热的因素。结果产前发热病因主要为感染性32例,占74.44%,其次为原因不明23例,占25.56%;感染性病因中:上呼吸道感染比率最高,占33.33%;观察组产前感染、贫血、妊娠糖尿病比率分别为74.44%、35.56%和23.33%,明显高于对照组(18.33%、11.11%、7.78%),差异均有统计学意义(P<0.05);Logistic回归分析结果显示:产前感染、妊娠糖尿病是产前发热的影响因素(OR=2.440和1.542,P<0.05);观察组早产、羊水污染、宫内窘迫、新生儿窒息和新生儿黄疸发生比率分别为25.56%、18.89%、23.33%、25.56%和37.78%,明显高于对照组(7.78%、5.56%、6.11%、5.56%、13.89%),差异均有统计学意义(P<0.05);观察组感染性发热产妇胎膜早破、羊水污染和新生儿窒息发生比率分别为37.31%、25.37%和31.34%,明显高于非感染性发热产妇(13.04%、0、8.70%),差异均有统计学意义(P<0.05)。结论产前发热病因以感染性为主,其影响因素包括产前感染及妊娠糖尿病,其对妊娠结局及新生儿结局产生不良影响。Objective To explore the clinical characteristics and differential diagnosis of different causes of prenatal fever and the influence of intrauterine infectious prenatal fever on pregnancy outcome.Methods A retrospective study was conducted,from January 2018 to January 2021,90 pregnant women with prenatal fever were selected as the observation group,and 180 normal pregnant women were selected as the control group,the causes of prenatal fever in the observation group were analyzed,the differences of pregnancy outcome and neonatal outcome between the observation group and the control group,observation group infectious and non-infectious febrile parturients were compared.Factors affecting prenatal fever were analyzed using Logistic regression.Results The main cause of antenatal fever was infection in 32 cases,accounting for 74.44%,followed by 23 cases of unknown cause,accounting for 25.56%;Among infectious causes:upper respiratory tract infection accounted for the highest proportion,accounting for 33.33%;The proportions of prenatal infection,anemia and gestational diabetes mellitus in observation group were 74.44%,35.56%and 23.33%,respectively,which were significantly higher than those in control group(18.33%,11.11%,7.78%),the differences were statistically significant(P<0.05);Logistic regression analysis showed that prenatal infection and gestational diabetes mellitus were the influential factors of prenatal fever(OR=2.440 and 1.542,P<0.05);The incidence rates of premature delivery,amniotic fluid pollution,intrauterine distress,neonatal asphyxia and neonatal jaundice in the observation group were 25.56%,18.89%,23.33%,25.56%and 37.78%,respectively,which were significantly higher than those in the control group(7.78%,5.56%,6.11%,5.56%,13.89%),the differences were statistically significant(P<0.05);The incidence rates of premature rupture of membranes,amniotic fluid contamination and neonatal asphyxia in the infectious febrile women of observation group were 37.31%,25.37%and 31.34%,respectively,which were significantly

关 键 词：产前发热 病因 影响因素 妊娠结局 新生儿结局 

分 类 号：R714.2[医药卫生—妇产科学]