新冠肺炎核酸咽拭子采样影响因素分析  

Analysis of influencing factors of COVID-19 nucleic acid throat swab sampling

作　　者：颜微微 夏俊 邓可斌[2] 李辉[2] 雷西熙 姜锐[2] YAN Weiwei;XIA Jun;DENG Kebin;LI Hui;LEI Xixi;JIANG Rui(The First Clinical College,Hubei University of Chinese Medicine,Wuhan 430065,China)

机构地区：[1]湖北中医药大学第一临床学院,湖北武汉430065 [2]湖北省中医院耳鼻咽喉科,湖北武汉

出　　处：《中国中西医结合耳鼻咽喉科杂志》2021年第6期401-403,共3页Chinese Journal of Otorhinolaryngology in Integrative Medicine

摘　　要：目的探讨新冠肺炎(Coro-navirus Disease 2019,COVID-19)核酸咽拭子采样影响因素分析。方法选取2020年2月27~28日湖北省中医院光谷院区发热门诊发热病人121名(发热>37.3℃),伴或不伴干咳、乏力、鼻塞、流涕等症。其中男性67名,女性54名。20岁及以下11名,20~60岁71名,60岁及以上39名。所有患者均进行核酸咽拭子采样检测。由同一耳鼻喉科医师操作,用同一型号咽拭子先鼻咽部采样,再马上对同一患者予以口咽部采样。以检验科咽拭子阳性及阴性结果为评价指标。结果鼻咽拭子与口咽拭子总体阳性率两组间差异显著(P<0.05),而鼻咽拭子与口咽拭子阳性率分别在男女两组间无明显差异(P>0.05)。鼻咽拭子与口咽拭子阳性率分别在三组不同年龄组间亦无明显差异(P>0.05)。结论核酸咽拭子采样阳性率与患者年龄、性别无明显相关性,但与采样部位密切相关。其中鼻咽拭子阳性率明显较口咽拭子高。因此如需提高核酸采样准确性,建议可请相关专业医师如耳鼻喉医师来进行鼻咽拭子采样。Objective To investigate the influence factors of novel coronavirus pneumonia(Coro-navirus Disease 2019,COVID-19)nucleic acid throat swab sampling.Methods From February 27 to February 28,2020,121 patients(fever>37.3℃)with or without dry cough,fatigue,nasal obstruction and runty nose were selected.There were 67 males and 54 females.11 were aged 20 and below,71 were aged 20~60 and 39 were aged 60 and above.All patients underwent nucleic acid swab sampling and detection.The nasopharyngeal samples were taken by the same otolaryngologist with the same type of throat swab,and then the oropharyngeal samples were taken by the same patient immediatel.Results The overall positive rates of nasopharyngeal swabs and oropharyngeal swabs were significantly different between the two groups(P<0.05),while the positive rates of nasopharyngeal swabs and oropharyngeal swabs were not significantly different between male and female groups(P>0.05).There was no significant difference in the positive rate of nasopharyngeal swab and oropharyngeal swab in different age groups(P>0.05).Conclusion The positive rate of nucleic acid swab sampling has no obvious correlation with the patient's age and gender,but is closely related to the sampling site.The positive rate of nasopharyngeal swab was significantly higher than that of oropharyngeal swab.Therefore,to improve the accuracy of nucleic acid sampling,it is recommended to ask the relevant professional physician such as otolaryngologist to conduct nasopharyngeal swab sampling.

关 键 词：新冠肺炎 咽拭子采样 影响因素 阳性率 

分 类 号：R440[医药卫生—诊断学] R563.1[医药卫生—临床医学]