Hp感染对冠心病患者血脂代谢、血小板功能及冠脉狭窄程度的影响  

Effects of Hp infection on blood lipid metabolism,platelet function and severity of coronary stenosis in patients with coronary heart disease

作　　者：胡靖超[1] 范例[1] 卓杨[1] 黄欣[2] 王磊[2] 许左隽[1] HU Jing-chao;FAN Li;ZHUO Yang;HUANG Xin;WANG Lei;XU Zuo-jun(Department of Cardiology,The Ninth People's Hospital affiliated to Shanghai Jiao Tong University School of Medicine,Shanghai 200011,China)

机构地区：[1]上海交通大学医学院附属第九人民医院心血管内科,上海200011 [2]上海交通大学医学院附属第九人民医院消化内科,上海200011

出　　处：《武警后勤学院学报（医学版）》2021年第12期102-103,106,共3页Journal of Logistics University of PAP（Medical Sciences）

摘　　要：【目的】探讨幽门螺杆菌(Hp)感染对冠心病患者血脂代谢、血小板功能及冠脉狭窄程度的影响。【方法】选择我院2012年6月-2021年5月109例冠心病(CHD)患者作为研究对象,根据Hp感染情况分为感染组(n=49)和非感染组(n=60)。比较两组血脂代谢指标、血小板功能指标及冠脉狭窄程度。【结果】感染组LDL-C、TG、TC、CD63、CD62p、PAF水平高于非感染组(P<0.05);感染组冠状动脉狭窄程度低于非感染组(P<0.05)。【结论】Hp感染会显著加重CHD患者体内血脂代谢紊乱,影响血小板功能,并增加冠脉狭窄程度。【Objective】To explore the effects of Helicobacter pylori(Hp)infection on blood lipid metabolism,platelet function and severity of coronary stenosis in patients with coronary heart disease(CHD).【Methods】A total of 109 patients with CHD in the hospital between June 2012 and May 2021.According to presence or absence of Hp infection,they were divided into infection group(n=49)and non-infection group(n=60).【Results】levels of LDL-C,TG,TC,CD63,CD62p and PAF infection group were higher than those in non-infection group(P<0.05).coronary stenosis in infection group was lower than that in non-infection group(P<0.05).【Conclusion】Hp infection will aggravate disorders of blood lipid metabolism,affect platelet function and increase the severity of coronary stenosis in patients with CHD.

关 键 词：冠心病 幽门螺杆菌 血脂代谢 血小板功能 冠脉狭窄程度 

分 类 号：R543.3[医药卫生—心血管疾病]