影像学在神经内分泌肿瘤合并肝转移患者早期治疗评价中的作用:从解剖学到功能学  

Role of Imaging in Early Therapeutic Response Assessment for Neuroendocrine Neoplasm with Liver Metastasis:from Anatomical to Functional View

作　　者：高雨菡 王萱[1] 薛华丹[1] GAO Yuhan;WANG Xuan;XUE Huadan(Department of Radiology,PUMC Hospital,CAMS and PUMC,Beijing 100730,China)

机构地区：[1]中国医学科学院,北京协和医学院,北京协和医院放射科,北京100730

出　　处：《中国医学科学院学报》2021年第6期956-961,共6页Acta Academiae Medicinae Sinicae

基　　金：中国医学科学院医学与健康科技创新工程(2017-I2M-1-001)。

摘　　要：神经内分泌肿瘤病程中易发生肝转移。目前,神经内分泌肿瘤肝转移(NENLM)的治疗方法日益多样化,这使得过去单纯从形态学变化的角度评价其治疗效果具有一定的局限性。新兴的影像学生物标志物能够从功能层面描述肿瘤治疗相关的变化,为NENLM的疗效评价提供新的方法和思路。本文主要总结影像学评价NENLM早期疗效的现状及研究进展,旨在为有效评价NENLM的早期疗效提供参考,并为进一步探索与NENLM早期疗效相关的生物标志物提供思路。Liver metastasis is not rare during the course of neuroendocrine neoplasms.The methods for treating neuroendocrine neoplasm with liver metastasis(NENLM)are diversifying,which exposes the limitations of the early therapeutic response assessment based on only morphological changes.The emerging imaging biomarkers can sensitively describe changes in response to treatment from the functional level,providing new ideas for the therapeutic response evaluation of NENLM.In this paper,we reviewed the status quo and the latest research progress of imaging assessment for early therapeutic response of NENLM,aiming to provide reference for assessing the response and further exploring the treatment-related biomarkers.

关 键 词：神经内分泌肿瘤 肝转移 功能影像学 早期疗效评价 

分 类 号：R445[医药卫生—影像医学与核医学]