结核性腹膜炎的临床现状及研究进展  

Clinical Status and Research Progress of Tuberculous Peritonitis

作　　者：张云华 朱盛华 ZHANG Yunhua;ZHU Shenghua(Department of Gastroenterology,Union Hospital,Tongji Medical College,Huazhong University of Science and Technology,Wuhan 430022,China;Department of Gastroenterology,the First Affiliated Hospital of Sun Yat-sen University,Guangzhou 510080,China)

机构地区：[1]华中科技大学同济医学院附属协和医院消化内科,武汉430022 [2]中山大学附属第一医院消化内科,广州510080

出　　处：《中国医学科学院学报》2021年第6期975-979,共5页Acta Academiae Medicinae Sinicae

基　　金：国家自然科学基金(81570555)。

摘　　要：结核性腹膜炎(TBP)是目前临床的主要肺外结核病之一,因临床特征不典型,需鉴别疾病种类多,目前检查手段有限,以致对其诊断存在很大困难,而延迟诊断造成病死率的明显增加。通过对当前TBP的研究现状进行分析后,发现对TBP诊断价值较高的有T细胞斑点试验、腹部CT、腹腔镜活检检查,而腹水超敏结核分枝杆菌和利福平耐药基因检测、腹水腺苷脱氨酶、全身正电子放射断层扫描CT的应用价值仍需进一步研究,血清CA125有助于判断抗结核治疗疗效。Tuberculous peritonitis(TBP)is currently one of the common manifestations of extrapulmonary tuberculosis.Due to the atypical clinical features,diverse types of diseases to be distinguished,and limited detection methods,TBP is difficult to be diagnosed and the fatality caused by delayed diagnosis increases significantly.We studied the current research status of TBP and found that T cells spot test,abdominal CT,and laparoscopic biopsy were of high diagnostic value for TBP.However,the application of ascites Xpert-MTB/RIF-ultra assay,ascites ADA,and whole-body positron emission tomography/computed tomography remained to be studied.Serum CA125 helps to judge the efficacy of anti-tuberculosis treatment.

关 键 词：结核性腹膜炎 T细胞斑点试验 腹水 影像学检查 腹腔镜 

分 类 号：R526[医药卫生—内科学] R442.5[医药卫生—临床医学]