缬沙坦联合叶酸治疗老年高血压肾病的效果  

The effect of valsartan combined with folic acid in the treatment of elderly hypertensive nephropathy

作　　者：周春仁 ZHOU Chun-ren(Department of Pharmacy,The People's Hospital of Linchuan District Fuzhou City,Fuzhou 344000,China)

机构地区：[1]抚州市临川区人民医院药剂科,江西抚州344000

出　　处：《吉林医学》2021年第12期2874-2876,共3页Jilin Medical Journal

摘　　要：目的:分析缬沙坦联合叶酸治疗老年高血压肾病的效果。方法:选择2017年1月~2020年1月老年高血压肾病患者共50例,随机分组,对照组的患者给予缬沙坦治疗,观察组则在对照组的基础上增加叶酸。比较两组血压达标的时间、住院接受治疗的天数、治疗前后患者血压监测水平、肾功能监测结果、临床治疗总有效率、不良反应。结果:观察组血压达标的时间、住院接受治疗的天数、治疗后患者血压监测水平、肾功能监测结果、临床治疗总有效率均优于对照组,差异有统计学意义(P<0.05)。两组不良反应比较,差异无统计学意义(P>0.05)。结论:缬沙坦联合叶酸治疗老年高血压肾病的效果确切,可有效改善患者临床症状,并改善患者的血压和肾功能,且安全性高,无明显的不良反应,值得临床推广和应用。Objective To analyze the effect of valsartan combined with folic acid in the treatment of elderly hypertensive nephropathy.Method A total of 50 elderly patients with hypertensive nephropathy admitted to our hospital from January 2017 to January 2020 were enrolled in randomized groups.Patients in the control group were treated with valsartan,and the observation group was added with folic acid on the basis of the control group.The time to reach the target blood pressure,the number of days in hospital for treatment,the blood pressure monitoring level of the patients before and after treatment,the results of renal function monitoring,the total effective rate of clinical treatment,and adverse reactions were compared between the two groups.Results The time to reach the target blood pressure,the number of days in hospital for treatment,the blood pressure monitoring level of the patients after treatment,the results of renal function monitoring,and the total effective rate of clinical treatment in the observation group were better than those in the control group(P<0.05).There was no significant difference in adverse reactions between the two groups(P>0.05).Conclusion Sartan combined with folic acid has a definite effect in the treatment of elderly hypertensive nephropathy.It can effectively improve the clinical symptoms of patients and improve the blood pressure and renal function of the patients.It has high safety and no obvious side effects.It is worthy of promotion and application.

关 键 词：缬沙坦联合叶酸 老年高血压肾病 效果 

分 类 号：R544.1[医药卫生—心血管疾病] R692[医药卫生—内科学]