磁性金纳米复合物的合成及其在诊断治疗中的应用  

Synthesis of Magnetic Gold Nanocomposites and Its Application in Diagnosis and Treatment

作　　者：尹梁澜 兰晓莉[1] 张永学[1] 覃春霞[1] Yin Lianglan;Lan Xiaoli;Zhang Yongxue(Department of Nuclerr Medicine Union Hospital,Tongji Medical College,Huazhong University of Science and Technology,Hubei Key Laboratory of Molecular Imaging,Wuhan 430022,China)

机构地区：[1]华中科技大学同济医学院附属协和医院核医学科,分子影像湖北省重点实验室,武汉430022

出　　处：《华中科技大学学报（医学版）》2021年第6期788-792,共5页Acta Medicinae Universitatis Scientiae et Technologiae Huazhong

基　　金：国家自然科学基金资助项目(No.81401444,No.81873906)。

摘　　要：磁性金纳米是一种新型的多功能纳米复合物,可通过种子生长法、微乳液法、自组装法、化学还原法等方法合成球形、哑铃形、棒状、多面立方体形以及花形等多种形态的磁性金纳米粒。磁性金纳米兼具了磁性纳米材料的磁性、超顺磁性以及金纳米材料的等离子共振特性,在生物传感器、影像诊断、纳米载药、光热治疗以及作为诊疗一体剂等多个领域有广泛的应用。Magnetic gold nanoparticles is a new type of multifunctional nanocomposite.Different shapes of magnetic gold nanoparticles such as spherical,dumbbell,nanorod,polyhedron,nanoflower and multilayer structure,can be synthesized by seed growth,microemulsion,self-assembly or chemical reduction method,etc.Magnetic gold nanoparticles combine the superparamagnetism of magnetic nanomaterials and the plasma resonance properties of gold nanoparticles,which can be widely used in biosensors,catalysis,imaging diagnostics,nanoparticle drug delievery,photothermal therapy and theranostics.

关 键 词：磁性金纳米复合物 诊断 治疗 诊疗一体化 

分 类 号：R81[医药卫生—放射医学]