犬乳腺肿瘤化学治疗药物的研究进展  

Progress in research on chemotherapeutic drugs for canine breast tumor

作　　者：姜惠心 祁子泰 高修歌[1,2] 郭大伟[1,2] 季辉[1,2] 彭麟[1,2] 江善祥[1,2] JIANG Huixin;QI Zitai;GAO Xiuge;GUO Dawei;JI Hui;PENG Lin;JIANG Shanxiang(College of Veterinary Medicine,Nanjing Agricultural University,Nanjing 210095,China;Center for Veterinary Drug Research and Evaluation,Nanjing Agricultural University,Nanjing 210095,China)

机构地区：[1]南京农业大学动物医学院,江苏南京210095 [2]南京农业大学兽药研究评价中心,江苏南京210095

出　　处：《畜牧与兽医》2021年第12期116-122,共7页Animal Husbandry & Veterinary Medicine

摘　　要：犬乳腺肿瘤是兽医临床中犬最常见的肿瘤之一,严重威胁犬只健康。手术结合化学疗法是治疗犬乳腺肿瘤的主要方法,然而我国尚未批准用于兽医临床的抗犬乳腺肿瘤化学治疗药物。犬乳腺肿瘤与人乳腺肿瘤共享部分发病机制,科学合理的将人用抗乳腺癌药物转为犬用药物为解决宠物临床用药短缺带来新的途径。为加快犬乳腺肿瘤药物的研发,有必要对犬乳腺瘤相关药物进行综述。本文在概括犬乳腺肿瘤化疗用药现状的基础上,重点综述了近年来国内外抗犬乳腺肿瘤药物的研究进展,以期为犬乳腺肿瘤药物的创制提供思路与借鉴。Canine mammary tumorisone of the most common tumors in veterinary clinics, which seriously threatens the health of dogs. Surgical treatment combined with chemotherapy is the main approach to the treatment of canine mammary tumors.However, China has not yet approved any chemotherapeutic drugs for canine breast cancer for veterinary clinical use. Since canine mammary tumors and human breast tumors share part of the pathogenesis, the scientific and reasonable conversion of anti-human breast cancer drugs to canine drugs provides a new way to solve the shortage of pet clinical drugs.To accelerate the research on and development of canine mammary tumor drugs, it is necessary to review the research results on chemotherapeutic drugs for canine breast tumor. By summarizing the current status of chemotherapeutic drugs for canine mammary tumors, this review focuseson the progress in research onanti-canine mammary tumor drugs both at home and abroad in recent years, and provides ideas and references for development of canine mammary tumor drugs.

关 键 词：犬乳腺肿瘤 化学治疗药物 宠物药品 药物开发 

分 类 号：S858.292[农业科学—临床兽医学]