江西省社区居民心血管疾病二级预防用药情况分析  

Analysis of secondary prevention medication use for cardiovascular disease among community residents in Jiangxi Province

作　　者：徐艳[1] 颜玮[1] 刘杰[1] 熊小玲[2] 陈轶英[1] 陈小娜 许立平[1] XU Yan;YAN Wei;LIU Jie;XIONG Xiao-ling;CHEN Yi-ying;CHEN Xiao-na;XU Li-ping(Institute of Chronic Disease Prevention,Jiangxi Provincial Center for Disease Control and Prevention,Nanchang,Jiangxi 330029,China;不详)

机构地区：[1]江西省疾病预防控制中心慢防所,江西南昌330029 [2]江西省肿瘤医院癌症中心办公室,江西南昌330029

出　　处：《现代预防医学》2021年第24期4467-4470,4475,共5页Modern Preventive Medicine

基　　金：中央财政转移支付地方卫生计生服务项目(财社[2018]164号);江西省卫计委科技计划项目(20186009,202110114)。

摘　　要：目的评估江西省社区人群中心血管疾病患者的二级预防用药情况,明确其与个体特征之间的关系。方法选取江西省10个县(区)年龄在35~75岁的常住居民,通过问卷调查的方式收集研究对象自报缺血性心脏病(IHD)或缺血性脑卒中(IS)患病以及药物使用情况。采用多变量混合效应模型评估个体特征与二级预防用药治疗的相关性。结果在138632名调查对象中,2.1%(2956名)报告患者有IHD和/或IS史;患者报告使用抗血小板药物和/或他汀类药物的比例为11.3%(8.9%使用抗血小板药物,5.5%使用他汀类药物,3.0%两种药物均使用)。多因素分析结果显示,女性(OR=0.66,95%CI:0.47~0.92)、诊断心血管疾病>7年(OR=0.51,95%CI:0.32~0.83)的调查对象服用抗血小板药物或他汀类药物的可能性更低,年老(55~<64岁:OR=4.48,95%CI:1.02~19.57;65~<75岁:OR=5.17,95%CI:1.18~22.59)、教育程度越高(初中:OR=1.94,95%CI:1.36~2.76;大学及以上:OR=2.57,95%CI:1.01~6.54)的调查对象服用抗血小板药物或他汀类药物的可能性更高。结论江西省目前社区心血管疾病患者二级预防药物使用率低,女性、年轻人、受教育程度低以及病程长的心血管疾病患者是重点关注的对象。Objective To assess the secondary prevention medication use among patients with cardiovascular disease in a community-based population in Jiangxi Province and to clarify the relationship between medication use and individual characteristics. Methods Permanent residents aged 35-75 years in 10 counties(districts) of Jiangxi Province were selected,and self-reported ischemic heart disease(IHD) or ischemic stroke(IS) prevalence and medication use were collected through questionnaire. A multivariate mixed-effects model was used to assess the association between individual characteristics and secondary prevention medication treatment. Results Of 138 632 respondents, 2.1%(2 956) reported a history of IHD and/or IS;the proportion of patients reporting use of antiplatelet agents and/or statins was 11.3%(8.9% used antiplatelet agents,5.5% used statins, and 3.0% used both drugs). Multifactorial analysis showed that female respondents(OR=0.66, 95% CI:0.47-0.92) with a diagnosis of cardiovascular disease >7 years(OR=0.51, 95%CI: 0.32-0.83) were less likely to be taking antiplatelet agents or statins. Respondents with older age(55 to <64 years: OR=4.48, 95%CI: 1.02-19.57;65 to <75 years:OR=5.17, 95%CI: 1.18-22.59) and higher educational level(junior high school: OR=1.94, 95%CI: 1.36-2.76;university and above: OR=2.57, 95%CI: 1.01-6.54) were more likely to take antiplatelet agents or statins. Conclusion The rate of secondary prevention medication use among community patients with cardiovascular disease in Jiangxi Province is low, and females,young adults, those with low education, and those with long disease course should be paid attention to.

关 键 词：心血管疾病 二级预防 抗血小板药物 他汀类药物 

分 类 号：R54[医药卫生—心血管疾病]