益母生化汤联合地屈孕酮治疗宫腔镜子宫内膜息肉切除术后患者的疗效观察  

Observation on Curative Effect of Yimu Shenghua Decoction Combined with Dydrogesterone in Treating Patients after Hysteroscopic Endometrial Polypectomy

作　　者：陈兰[1] CHEN Lan(Changzhou Municipal Hospital of Traditional Chinese Medicine,Changzhou 213003 Jiangsu,China)

机构地区：[1]常州市中医医院,江苏常州213003

出　　处：《广州中医药大学学报》2021年第11期2377-2381,共5页Journal of Guangzhou University of Traditional Chinese Medicine

基　　金：南京中医药大学技术开发项目(编号:2017005)。

摘　　要：【目的】观察益母生化汤联合地屈孕酮治疗子宫内膜息肉宫腔镜术后患者的临床疗效,为临床治疗提供新的思路和方法。【方法】将770例子宫内膜息肉宫腔镜术后患者随机分为研究组和对照组,每组各385例。对照组仅给予3个疗程(每疗程为10 d)地屈孕酮治疗,研究组在益母生化汤治疗1周后,再给予3个疗程地屈孕酮治疗。观察2组患者的阴道出血时间、子宫内膜厚度、子宫内膜息肉复发情况及不良反应发生情况。【结果】(1)与对照组比较,研究组的阴道出血时间明显缩短,子宫内膜厚度明显变薄,差异均有统计学意义(P<0.05)。(2)经随访1年,研究组的复发率为5.45%(21/385),明显低于对照组的11.16%(43/385),差异有统计学意义(P<0.05)。(3)研究组的不良反应发生率为3.12%(12/385),对照组为2.60%(10/385),组间比较,差异无统计学意义(P>0.05)。【结论】运用益母生化汤联合地屈孕酮治疗子宫内膜息肉宫腔镜术后患者疗效确切,能明显缩短阴道出血时间,改善子宫内膜情况,显著降低子宫内膜息肉的复发。Objective To observe the clinical effect of Yimu Shenghua Decoction combined with dydrogesterone in treating patients after hysteroscopic endometrial polypectomy, so as to provide new ideas and methods for the clinical treatment. Methods A total of 770 cases of patients after hysteroscopic endometrial polypectomy were randomly divided into study group and control group,385 cases in each group. The control group was only given3 courses of dydrogesterone treatment(each course lasting 10 days),and the study group was given 3 courses of dydrogesterone treatment after one-week treatment with Yimu Shenghua Decoction. The time of vaginal bleeding,endometrial thickness,recurrence of endometrial polyps and the incidence of adverse reactions in the two groups were observed. Results(1)Compared with the control group,the duration of vaginal bleeding in the study group was significantly shortened, the endometrial thickness became thinner, and the difference was statistically significant(P<0.05).(2)After one-year follow-up,the recurrence rate of endometrial polyps in the study group was 5.45%(21/385),which was significantly lower than that in the control group(11.16%,43/385),and the difference was statistically significant(P<0.05).(3)The incidence of adverse reactions was 3.12%(12/385)in the study group and was 2.60%(10/385)in the control group,and the difference between the two groups was not statistically significant(P>0.05). Conclusion The application of Yimu Shenghua Decoction combined with drogesterone has certain curative effect in treating patients with hysteroscopic endometrial polypectomy,which can significantly shorten the time of vaginal bleeding,improve the endometrial condition,and significantly reduce the recurrence of endometrial polyps.

关 键 词：益母生化汤 地屈孕酮 宫腔镜 子宫内膜息肉切除术 阴道出血时间 子宫内膜厚度 复发情况 

分 类 号：R271.9[医药卫生—中西医结合]