腔内射频闭合术在大隐静脉曲张治疗中的应用  

Application of intracavity radiofrequency closure in the treatment of varicose of great saphenous vein

作　　者：滕哈乐 崔水森 李志坚 董建德 蔡红丽 黄金洪 TENG Hale;CUI Shuisen;LI Zhijian;DONG Jiande;CAI Hongli;HUANG Jinhong(Department of Cardiovascular Surgery,Capital Medical University Electric Power Teaching Hospital,Beijing100073,China;Health Management Center,Capital Medical University Electric Power Teaching Hospital,Beijing100073,China)

机构地区：[1]首都医科大学电力教学医院心脏血管外科,北京100073 [2]首都医科大学电力教学医院健康管理中心,北京100073

出　　处：《中国医药导报》2021年第35期133-137,共5页China Medical Herald

基　　金：北京电力医院科研项目(Y2021001)。

摘　　要：目的探讨腔内射频闭合术治疗大隐静脉曲张的应用价值。方法选取2019年6月至2020年6月首都医科大学电力教学医院收治的126例大隐静脉曲张患者,使用随机数字表法将其分为对照组和观察组(各63例)。对照组行传统手术,观察组行腔内射频闭合术治疗。比较两组治疗效果、围手术期指标、术后12 h的血流动力学指标。比较两组术前和术后1周的炎症因子水平,比较两组术前和术后6个月的静脉临床严重程度评分。随访1年,观察两组不良反应发生情况。结果观察组的术中出血量低于对照组,手术时间、术后下床时间及住院时间短于对照组,差异有统计学意义(P<0.05)。两组术后12 h的经皮动脉血氧饱和度、心率、平均动脉压水平比较,差异无统计学意义(P>0.05)。两组术后1周的血清肿瘤坏死因子-α、白细胞介素-6、基质金属蛋白酶-13水平低于术前,且观察组低于对照组,差异有统计学意义(P<0.05)。两组术后6个月静脉临床严重程度评分低于术前,且观察组低于对照组,差异有统计学意义(P<0.05)。两组治疗效果比较,差异无统计学意义(P>0.05)。两组深静脉血栓形成、皮下血肿、静脉炎、隐神经损伤、色素沉着、静脉曲张复发发生率比较,差异无统计学意义(P>0.05)。观察组切口感染/愈合不良、大腿段血肿发生率低于对照组,差异有统计学意义(P<0.05)。结论腔内射频闭合术治疗大隐静脉曲张能够有效缓解下肢静脉症状,减轻机体炎症状态,并且手术创伤小、术中出血少、并发症少,临床疗效确切,安全性高。Objective To evaluate the value of intracavity radiofrequency closure in the treatment of varicose of great saphenous vein.Methods A total of 126 patients with varicose of great saphenous vein admitted to Electric Power Teaching Hospital of Capital Medical University from June 2019 to June 2020 were selected.They were divided into control group and observation group(63 cases in each group)by random number table method.The control group received traditional surgery,and the observation group received intracavity radiofrequency closure.The therapeutic effect,perioperative indicators,and hemodynamic indexes 12 hours after surgery were compared between the two groups.The levels of inflammatory factors were compared between the two groups before surgery and one week after surgery,and the venous clinical severity score were compared between the two groups before surgery and six months after surgery.The two groups were followed up for one year to observe the incidence of adverse reactions.Results The amount of intraoperative blood loss in the observation group was lower than that in the control group,and the surgery time,postoperative time out of bed,and hospital stay were shorter than those in the control group,with statistical significances(P<0.05).There were no significant differences in percutaneous arterial oxygen saturation,heart rate,and mean arterial pressure between the two groups at 12 hours after surgery(P>0.05).Serum levels of tumor necrosis factor-α,interleukin-6,and matrix metalloproteinase-13 in two groups one week after operation were lower than those before surgery,and the observation group was lower than the control group,the differences were statistically significant(P<0.05).The venous clinical severity scores at six months after surgery was lower than that before surgery,and the observation group was lower than the control group,the differences were statistically significant(P<0.05).There was no significant difference in treatment effect between the two groups(P>0.05).There was no significant differe

关 键 词：大隐静脉曲张 腔内射频闭合术 血流动力学 

分 类 号：R543.6[医药卫生—心血管疾病]