舒芬太尼联合布比卡因的蛛网膜下腔注射在剖宫产手术中的应用研究  

Application study of subarachnoid injection of sufentanil combined with bupivacaine in cesarean section

作　　者：张宝华 ZHANG Baohua(Department of Anesthesiology,Jiujiang Maternal and Child Health Hospital,Jiujiang,Jiangxi,332000,China)

机构地区：[1]九江市妇幼保健院麻醉科,江西九江332000

出　　处：《当代医学》2022年第1期62-64,共3页Contemporary Medicine

摘　　要：目的探讨舒芬太尼联合布比卡因的蛛网膜下腔注射在剖宫产手术中的应用效果。方法回顾性分析本院2018年1月至2019年12月收治的100例剖宫产产妇的临床资料,按照麻醉方式的不同分为观察组(n=52)与对照组(n=48),观察组予以舒芬太尼联合布比卡因蛛网膜下腔注射麻醉,对照组予以布比卡因蛛网膜下腔注射麻醉。比较两组给药后3 min(T0)、给药后10 min(T1)、术毕(T2)平均动脉压(MAP)与心率(HR)变化情况及围术期产妇不良事件发生情况、新生儿Apgar评分。结果 T0、T1及T2时,两组MAP与HR水平比较差异均无统计学意义;观察组不良事件发生率低于对照组,差异有统计学意义(P<0.05);两组新生儿Apgar评分比较差异无统计学意义。结论剖宫产手术产妇采用舒芬太尼联合布比卡因蛛网膜下腔注射麻醉效果确切,可有效降低产妇围术期不良事件发生率,值得临床推广应用。Objective To investigate the effect of subarachnoid injection of sufentanil combined with bupivacaine in cesarean section. Methods A retrospective analysis of the clinical data of 100 women undergoing cesarean section in our hospital from January 2018 to December 2019 were divided into observation group(n=52) and control group(n=48) according to different methods of anesthesia. The observation group was anesthetized with sufentanil combined with subarachnoid injection of bupivacaine, and the control group was anesthetized with subarachnoid injection of bupivacaine. The changes of mean arterial pressure(MAP) and heart rate(HR) at 3 min(T0), 10 min(T1), and post-operative(T2) after administration, the occurrence of perioperative maternal adverse events and newborns Child Apgar score were compared between the two groups. Results At T0, T1 and T2, there was no statistically significant difference in the levels of MAP and HR between the two groups;the incidence of adverse events in the observation group was lower than that in the control group, and the difference was statistically significant(P<0.05);the difference in Apgar scores between the two groups of newborns was not statistically significant. Conclusion The effect of sufentanil combined with subarachnoid injection of bupivacaine for parturients undergoing cesarean section is effective, which can effectively reduce the incidence of perioperative adverse events in parturients, and is worthy of clinical application.

关 键 词：剖宫产手术 舒芬太尼 布比卡因 蛛网膜下腔注射 不良事件 

分 类 号：R614[医药卫生—麻醉学]