乳腺癌患者首次日间化疗并发症预警模型的应用  

Application of complication early warning model in breast cancer patients undergoing day chemotherapy for the first time

作　　者：陈秀华[1] 王芳[2] 王以浪 蔡鑫雨 佘网娟 杨海霞 季建红[3] CHEN Xiuhua;WANG Fang;WANG Yilang;CAI Xinyu;SHE Wangjuan;YANG Haixia;JI Jianhong(Department of Oncology,Second Affiliated Hospital of Nantong University,Nantong,Jiangsu province,226001,China)

机构地区：[1]江苏省南通大学第二附属医院肿瘤科,江苏省南通市226001 [2]江苏省南通大学第二附属医院护理部,江苏省南通市226001 [3]江苏省南通大学第二附属医院重症监护室,江苏省南通市226001 [4]南通市肿瘤医院肿瘤内科

出　　处：《中国护理管理》2021年第12期1876-1880,共5页Chinese Nursing Management

基　　金：南通市科学技术局2019年科研计划项目(MSZ19079)。

摘　　要：目的:评价化疗并发症预警模型在乳腺癌首次日间化疗患者中的应用效果。方法:选取2020年1月-12月某三级甲等医院肿瘤内科日间病房收治的乳腺癌首次化疗患者86例为研究对象,按照入院时间分为对照组(42例)和实验组(44例)。实验组在出院后第2~14天通过手机采用化疗并发症预警模型护理信息平台+电话随访的方式进行干预,对照组给予常规电话随访+咨询指导。采用并发症事件评价标准CTCAE 4.0、乳腺癌患者生活质量测定量表比较两组的干预效果。结果:实验组化疗间歇期白细胞计数降低、血小板计数降低、呕吐并发症的程度分级优于对照组,差异有统计学意义(P<0.05);实验组干预后便秘的程度分级优于干预前,差异有统计学意义(P<0.05)。实验组乳腺癌患者生活质量总得分为(112.73±4.33)分,高于对照组,差异有统计学意义(P<0.05)。结论:乳腺癌患者日间化疗间歇期通过化疗并发症预警模型进行干预,部分化疗并发症程度分级得到改善,生活质量有所提高,值得临床推广应用。Objective:To evaluate the effect of complication early warning model in breast cancer patients undergoing day chemotherapy for the first time.Methods:A total of 86 patients with breast cancer who received chemotherapy for the first time in the oncology internal medicine day ward from January to December 2020 were selected,and divided into control group(n=42)and experimental group(n=44)according to the admission time.In the experimental group,the early warning model of chemotherapy complications nursing information platform was used from the second day to the fourteenth day after discharge,while the control group was given routine telephone follow-up and consultation guidance.The intervention effect of the two groups was compared with the Common Terminology Criteria for Adverse Events 4.0 and the quality of life of breast cancer patients.Results:The grade of complications during intermission of chemotherapy in the experimental group were lower than that of the control group,and the grade of leucopenia,thrombocytopenia,vomiting were significantly lower than that of the control group(P<0.05).The grade of constipation in the experimental group was significantly lower after the intervention(P<0.05).The quality of life of breast cancer patients in the experimental group(112.73±4.33)was higher than the control group(P<0.05).Conclusion:The chemotherapy complications warning model can lower the grade of chemotherapy complications in breast cancer patients during intermission of chemotherapy,improve the quality of life,and worthy of clinical promotion.

关 键 词：乳腺癌 化疗 并发症 预警模型 日间病房 

分 类 号：R47[医药卫生—护理学] R197[医药卫生—临床医学]