布地奈德联合尼美舒利治疗急性上呼吸道感染的效果及对炎性指标影响  

Effect of Budesonide Combined with Nimesulide in the Treatment of Acute Upper Respiratory Tract Infection and Its Impact on Inflammatory Indicators

作　　者：牛莎[1] 余嗣崇[1] NIU Sha;YU Sichong(Respiratory Intensive Care Unit,Jiaozuo Second People's Hospital,Jiaozuo 454000,China)

机构地区：[1]焦作市第二人民医院呼吸与危重症医学科,河南焦作454000

出　　处：《临床医学工程》2021年第12期1665-1666,共2页Clinical Medicine & Engineering

摘　　要：目的探讨布地奈德联合尼美舒利治疗急性上呼吸道感染的效果及对炎性指标的影响。方法92例急性上呼吸道感染患者按治疗方法的不同分为两组各46例,对照组给予布地奈德治疗,实验组给予布地奈德联合尼美舒利治疗,比较两组的治疗效果、症状缓解时间及炎性指标水平。结果实验组的治疗总有效率为95.65%,高于对照组的80.43%(P<0.05)。实验组的各项症状缓解时间均短于对照组(P<0.05)。治疗后,实验组的IL-6、CRP及TNF-α水平均低于对照组(P<0.05)。结论布地奈德联合尼美舒利治疗急性上呼吸道感染的效果显著,有助于减轻患者机体炎性反应,促进临床症状缓解。Objective To explore the effect of budesonide combined with nimesulide in the treatment of acute upper respiratory tract infection and its impact on inflammatory indicators.Methods 92 patients with acute upper respiratory tract infection were divided into two groups according to different treatment methods,with 46 cases in each group.The control group was treated with budesonide,and the experimental group was treated with budesonide combined with nimesulide.The therapeutic effect,symptom remission time and levels of inflammatory indicators were compared between the two groups.Results The total effective rate of treatment in the experimental group was 95.65%,higher than 80.43%in the control group(P<0.05).The remission time of symptoms in the experimental group were shorter than those in the control group(P<0.05).After treatment,the levels of IL-6,CRP and TNF-α in the experimental group were lower than those in the control group(P<0.05).Conclusions Budesonide combined with nimesulide in the treatment of acute upper respiratory tract infection has significant effect,which helps to reduce the inflammatory response of patients and promote the remission of clinical symptoms.

关 键 词：急性上呼吸道感染 布地奈德 尼美舒利 炎性指标 

分 类 号：R56[医药卫生—呼吸系统]