聚醚醚酮与钛网在颅骨修补术中的应用分析  

Analysis of application of polyetheretherketone and titanium mesh in cranioplasty

作　　者：曾春[1,2] 金柯含 李凯 梁剑峰 张俊 牛文超 武亚军[4] 徐珑 刘伟明[1] Zeng Chun;Jin Kehan;Li Kai;Liang Jianfeng;Zhang Jun;Niu Wenchao;Wu Yajun;Xu Long;Liu Weiming(Department of Neurosurgery,Beijing Tiantan Hospital,Capital Medical University,Beijing 100070,China;Department of Neurosurgery,Peking University International Hospital,Beijing 102206,China;Department of Neurology,Peking University International Hospital,Beijing 102206,China;Department of Operation,Peking University International Hospital,Beijing 102206,China)

机构地区：[1]首都医科大学附属北京天坛医院神经外科,100070 [2]北京大学国际医院神经外科,102206 [3]北京大学国际医院神经内科,102206 [4]北京大学国际医院手术室,102206

出　　处：《中华神经外科杂志》2021年第12期1219-1222,共4页Chinese Journal of Neurosurgery

摘　　要：目的比较聚醚醚酮(PEEK)与钛网在颅骨修补术中的临床应用效果和安全性。方法回顾性分析2015年10月至2021年2月北京大学国际医院神经外科收治的58例行颅骨修补术患者的临床资料。根据其应用的修补材料分为PEEK组(17例)和钛网组(41例),比较两组患者的经济学指标(住院时间、住院费用)、有效性(塑形满意度)和安全性指标(术后并发症发生情况)。结果PEEK组患者的年龄小于钛网组[(32.1±3.8)岁对比(40.7±2.2)岁,P=0.044]。PEEK组的总住院时间长于钛网组[(25.1±2.9)d对比(16.4±1.1)d,P=0.002]。PEEK组患者住院费用明显高于钛网组[(212085±19635)元对比(76514±5937)元,P=0.001]。PEEK组患者的塑形满意比例高于钛网组(16/17对比28/41,P=0.036)。两组间并发症发生比例的差异无统计学意义(2/17对比5/41,P=0.964)。两组间术后第1天血白细胞计数和中性粒细胞占比的差异均无统计学意义(均P>0.05)。结论颅骨修补术应用PEEK患者的经济学指标不及应用钛网的患者,而有效性好于后者,可作为颅骨修补术中选择的材料之一。Objective To investigate the clinical outcomes and safety of polyetheretherketone(PEEK)and titanium mesh in cranioplasty.Methods The clinical data of 58 patients who were admitted to the Department of Neurosurgery of Peking University International Hospital and underwent cranioplasty from October 2015 to February 2021 were retrospectively analyzed.According to the repair materials used,the patients were divided into PEEK group(17 cases)and titanium mesh group(41 cases).The economic indicators(length of hospital stay,hospitalization cost),effectiveness(sculpting satisfaction)and safety(occurrence of postoperative complications)were compared between the two groups.Results Patients in the PEEK group were younger than those in the titanium mesh group(32.1±3.8 years vs.40.7±2.2 years,P=0.044).Length of hospital stay in the PEEK group was significantly longer than that in the titanium mesh group(25.1±2.9 days vs.16.4±1.1 days,P=0.002).The hospitalization cost of PEEK group was higher compared with that of titanium mesh group(212085±19635 yuan vs.76514±5937 yuan,P=0.001).The patient′s rate of satisfaction with cranioplasty in the PEEK group was significantly higher than that in the titanium mesh group(16/17 vs.28/41,P=0.036).The incidences of postoperative complications were comparable between the two groups(2/17 vs.5/41,P=0.964).There was no significant difference in postoperative white blood cell count or neutrophil percentage between the two groups on the first day post operation(both P>0.05).Conclusions The outcome of PEEK for cranioplasty is better than that of titanium mesh,while its economic indicators are not as good as the latter.PEEK can be used as one of the materials of choice in cranioplasty.

关 键 词：减压颅骨切除术 治疗结果 安全性 聚醚醚酮 钛网 

分 类 号：R651.1[医药卫生—外科学]