改良双腔球囊导管介入再通治疗输卵管阻塞致不孕不育患者的临床效果及相关因素分析  

Clinical effect and related factors analysis of modified double-lumen balloon catheter interventional recanaliza⁃ tion in the treatment of infertility caused by tubal obstruction

作　　者：崔晓剑 陈明高[1] CUI Xiaojian;CHEN Minggao(Department of Inter-ventional Imaging,Jinhua People's Hospital,Jinhua 321000,China)

机构地区：[1]金华市人民医院影像介入科,浙江金华321000

出　　处：《全科医学临床与教育》2021年第12期1108-1111,共4页Clinical Education of General Practice

摘　　要：目的探究改良双腔球囊导管介入治疗输卵管阻塞致不孕不育患者的临床效果及影响受孕结果的相关因素。方法回顾性收集输卵管阻塞致不孕不育患者100例为研究对象,50例行常规双导丝再通术为对照组,50例行改良双腔球囊导管介入再通治疗为观察组,比较两组患者术后临床效果,并分析影响受孕与非受孕结果的相关因素。结果观察组插管成功率明显高于对照组(χ^(2)=6.21,P<0.05);两组患者均未见严重术后不良反应及并发症;术后受孕患者雌二醇(E_(2))水平明显高于非受孕患者,促黄体生成素(LH)、促催乳素(PRL)、促卵泡素(FSH)水平明显低于非受孕患者(t分别=5.49、4.79、7.52、6.90,P均<0.05);经多因素logistic回归分析显示,E_(2)、LH、PRL、FSH、年龄、病程、盆腔感染病史、子宫内膜异位症、子宫肌瘤、月经异常、输卵管功能异常、辐射史均为患者输卵管阻塞介入治疗后受孕结果的危险因素(OR分别=3.21、2.59、3.26、2.57、5.12、4.22、4.27、4.23、5.12、2.31、4.04,P均<0.05)。结论改良双腔球囊导管辅助下导丝再通法可有效提升输卵管开口插管成功率;术后患者可通过检测血清E_(2)、LH、PRL、FSH水平,监测相关风险因素,辅助诊断与治疗。Objective To explore the clinical effect of modified double-lumen balloon catheter intervention in the treatment of infertility patients with tubal obstruction and related factors affecting pregnancy outcomes.Methods A retrospective collection of 100 patients with infertility caused by fallopian tube obstruction as the research object,50 patients underwent conventional double-guide wire recanalization as the control group,and 50 patients underwent modified double lumen balloon catheter interventional recanalization as the observation group.The clinical effects of the two group were compared,and the related factors that affect the results of pregnancy and non-pregnancy were analyzed.Results The success rate of in the observation group was significantly higher than that in the control group(χ^(2)=6.21,P<0.05),There was no serious postoperative adverse reactions and complications in the two groups.The level of estradiol(E_(2))in pregnant patients was significantly higher than that in non-pregnant patients,luteinizing hormone(LH),prolactin(PRL),and folli-cle stimulating hormone(FSH)levels were significantly lower than non-pregnant patients(t=5.49,4.79,7.52,6.90,P<0.05).Multivariate logistic regression analysis showed that E_(2),LH,PRL,FSH,age,course of disease,history of pelvic in-fection,endometriosis,uterine fibroids,menstrual abnormalities,abnormal fallopian tube function,and radiation history are all patients with tubal obstruction intervention risk factors for pregnancy outcomes after treatment(OR=3.21,2.59,3.26,2.57,5.12,4.22,4.27,4.23,5.12,2.31,4.04,P<0.05).Conclusion The modified double-lumen balloon catheter assis-ted guidewire recanalization method can effectively increase the success rate of tubal intubation,postoperative patients can detect serum E_(2),LH,PRL,FSH levels,monitor related risk factors,and assist in diagnosis and treatment.

关 键 词：输卵管阻塞 不孕 介入再通 改良双腔球囊导管 

分 类 号：R711.6[医药卫生—妇产科学]