硫化纳米零价铁与牛血清白蛋白相互作用的光谱学研究  

Spectroscopic Investigation on the Interaction of Sulfidated Nano Zerovalent Iron with Bovine Serum Albumin

作　　者：赵玲子[1] 菅琳晗 杨炳君[1] Zhao Lingzi;Jian Linhan;Yang Bingjun(College of Environmental Science and Engineering,Jilin Normal University,Siping 136000,China)

机构地区：[1]吉林师范大学环境科学与工程学院,吉林四平136000

出　　处：《山东化工》2021年第23期106-107,112,共3页Shandong Chemical Industry

摘　　要：硫化纳米零价铁(S-nZVI)是近年来兴起的一种应用于地下水原位修复的新型纳米铁基修复剂,其生物安全性日益受到社会的关注。通过紫外光谱和荧光光谱相互验证,研究羧甲基纤维素钠(CMC)稳定S-nZVI和牛血清白蛋白(BSA)的相互作用。结果表明,CMC-S-nZVI与牛血清白蛋白的作用较弱,牛血清白蛋白光谱特性的变化主要是由于其微环境的改变引起的。这将为从分子水平上研究CMC-S-nZVI的生物安全性提供理论依据。Sulfidated Nano Zerovalent Iron(S-nZVI)is a recent development related to the use of nano zerovalent iron(nZVI)based materials for groundwater remediation,and its biosafety has been increasingly concerned by the society.The interaction between S-nZVI stabilized by carboxymethyl cellulose(CMC)and bovine serum albumin(BSA)was studied by UV and fluorescence spectroscopy.The results showed that the interaction between CMC-S-nZVI and BSA was weak,and the change of spectral characteristics of BSA was mainly caused by the change of microenvironment.This paper will provide a theoretical basis for studying the biosafety of S-nZVI at molecular level.

关 键 词：硫化纳米零价铁(S-nZVI) 牛血清白蛋白(BSA) 荧光光谱 

分 类 号：O657.3[理学—分析化学]