不同脂肪纯化方法对乳腺手术后瘢痕疼痛的影响  

Effect of different fat purification methods on scar pain after breast surgery

作　　者：张旭[1] 隆建萍[1] 马秀芬[1] 张清霞[1] 毛红岩[1] 独晓燕[1] 杨涛[1] ZHANG Xu;LONG Jianping;MA Xiufen;ZHANG Qingxia;MAO Hongyan;DU Xiaoyan;YANG Tao(the First Department of Mammary Gland,Gansu Provincial Maternity and Child Care Hospital,Lanzhou,Gansu,730050)

机构地区：[1]甘肃省妇幼保健院乳腺一科,甘肃兰州730050

出　　处：《实用临床医药杂志》2021年第24期39-42,共4页Journal of Clinical Medicine in Practice

基　　金：甘肃省兰州市科学技术局项目(2018-3-28)。

摘　　要：目的通过不同脂肪获取及脂肪纯化方法,并采用自体脂肪移植术(AFG)治疗瘢痕相关疼痛,总结AFG在脂肪获取及提纯中的治疗经验。方法将115例研究对象随机分为治疗组(58例)和对照组(57例),治疗组进一步分为A组、B组、C组和D组。A组(n=16)采用干抽法和离心法,B组(n=13)采用干抽法和静置法,C组(n=14)采用湿抽法和离心法,D组(n=15)采用湿抽法和静置法,对照组57例患者无特殊治疗。观察AFG在瘢痕相关疼痛中的治疗效果,比较治疗前后视觉模拟评分法(VAS)评分和治疗后满意度调查情况,总结AFG在脂肪获取及提纯中的治疗经验。结果治疗后,A、B、C、D组VAS评分均较治疗前降低,且低于对照组,差异有统计学意义(P<0.001)。治疗组各组满意度评分均高于对照组,差异有统计学意义(P<0.001)。结论AFG技术在乳腺手术后瘢痕疼痛中的疗效显著。在脂肪获取过程中,是否注射肿胀液,选择离心法或静止法均不影响治疗效果。Objective To treat scar-related pain with Autologous fat transplantation(AFG) through different methods of fat acquisition and fat purification, sum up the treatment experience of AFG in fat acquisition and purification. Methods A total of 115 patients were randomly divided into treatment group(n=58) and control group(n=57), treatment group were further divided into groups A, B, C and D. The group A(n=16) received dry pumping and centrifugal method, the group B(n=13) received dry pumping and static method, the group C(n=14) received wet pumping and centrifugal method, and the group D(n=15) received wet pumping andstatic method. Patients in the control group(n=57) received no special treatment. The therapeutic effects of AFG in scar related pain were observed, the Visual Analog Scale(VAS) score before and after treatment and the satisfaction degree by survey after treatment were compared, and the therapeutic experience of AFG in fat acquisition and purification was summarized. Results After treatment, VAS scores of groups A, B, C and D were lower than those before treatment and the control group(P<0.001). The satisfaction scores of each group of the treatment group were higher than that of the control group(P<0.001). Conclusion AFG technique is effectivein scar pain after breast surgery. In the process of fat acquisition, injecting swelling fluid or not, centrifugal method or static method all have no influence on therapeutic effects.

关 键 词：自体脂肪移植 乳腺手术 瘢痕疼痛 脂肪纯化 临床疗效 

分 类 号：R61[医药卫生—外科学] R441.1[医药卫生—临床医学]