长白山二道白河区森林康养对人体免疫功能的影响  

Effects of Forest Therapy on Human Immunological Function in Erdaobaihe Area of Changbai Mountain

作　　者：刘艳波[1] 王焕琦[2] 王洪俊[3] 安丽萍[2] 范春楠[3] 包学英[4] 贾晓静[4] 李洁 黄琴扉 张玮尹 杜培革[2] Liu Yanbo;Wang Huanqi;Wang Hongjun;An Liping;Fan Chunnan;Bao Xueying;Jia Xiaojing;Li Jie;Huang Ch'infei;Chang Weiyin;Du Peige(Department of Pathophysiology,Medical College,Beihua University,Jilin 132013,China;Department of Biological Pharmacy,College of Pharmacy,Beihua University,Jilin 132013,China;Department of Ecological Architecture,College of Forestry,Beihua University,Jilin 132013,China;Affiliated Hospital,Beihua University,Jilin 132013,Jilin,China;Graduate Institute of Science Education and Environmental Education,"National"Kaohsiung Normal University,Kaohsiung 82444,Taiwan,China;College of Forestry,Fujian Agriculture and Forestry University,Fuzhou 350002,China)

机构地区：[1]北华大学基础医学院病理生理学教研室,吉林132013 [2]北华大学药学院生物制药教研室,吉林132013 [3]北华大学林学院生态园林教研室,吉林132013 [4]北华大学附属医院,吉林132013 [5]台湾高雄师范大学科学教育与环境教育研究所,高雄82444 [6]福建农林大学林学院,福州350002

出　　处：《中国城市林业》2021年第6期105-109,共5页Journal of Chinese Urban Forestry

基　　金：吉林省发展和改革委资助项目“长白山红松阔叶林森林环境与人体健康研究”(2020C035-3);企事业单位委托项目研究“长白山和平森林养生项目研究”(201801010);北华大学重点教研项目“森林康养课程在‘林+医’复合型人才培养中的作用”(XJZD2020061)。

摘　　要：为了探讨森林康养对人体免疫功能的影响,筛选12名健康志愿者于2019年7月上旬在吉林省长白山二道白河区森林康养基地进行为期"3天2夜"的康养活动。康养前后,利用流式细胞仪检测外周血CD56^(+)NK细胞和CD3^(+)淋巴细胞的百分比,通过酶联免疫吸附试验(ELISA)法测定血浆中颗粒酶、颗粒溶素和穿孔素的浓度。研究结果发现,长白山二道白河区夏季"3天2夜"的森林康养活动显著提高了外周血CD3^(+)淋巴细胞和CD56^(+)NK细胞的百分比(P<0.05),同时血浆中穿孔素、颗粒酶和颗粒溶素的水平增加(P<0.05)。由此可见,森林康养活动在一定程度上可提高人体免疫功能。To explore the effect of forest therapy in the summer on human immune function in Baihe District of Changbai Mountain,Jilin Province,the study screens and selects 12 healthy volunteers to have a three-day and two-night forest therapy there.The percentages of CD56^(+)NK cells and CD3^(+)lymphocytes in their peripheral blood are monitored using flow cytometry,and the concentrations of Grs,GNLY and perforin in plasma are tested using Elisa assay before and after forest therapy.The results show that compared with the pretest conditions,the forest therapy produces a significant increase in percentage of CD3^(+)lymphocytes and CD56^(+)NK cells(P<0.05),and also an obvious increase in the perforin,GrA,GrB and GNLY levels in plasma.The results suggest that forest therapy activities can significantly increase human immune function to a certain extent.

关 键 词：森林康养 NK细胞 淋巴细胞 免疫活性 长白山 

分 类 号：S788.1[农业科学—林学]