偶发分枝杆菌致感染性肉芽肿一例  

Infectious granuloma due to Mycobacterium fortuitum:a case report

作　　者：陈祚玺 王娜[2] 于长平[2] 施仲香[2] 潘晴[2] 暴芳芳[2] 卢宪梅[2] 王真真[2] 刘红[2] 张福仁[2] CHEN Zuoxi;WANG Na;YU Changping;SHI Zhongxiang;PAN Qing;BAO Fangfang;LU Xianmei;WANG Zhenzhen;LIU Hong;ZHANG Furen(Cheeloo College of Medicine,Shandong University,Jinan 250012,China;Shandong Provincial Hospital for Skin Diseases&Shandong Provincial Institute of Dermatology and Venereology,Shandong First Medical University,Jinan 250022,China)

机构地区：[1]山东大学齐鲁医学院,山东济南250012 [2]山东第一医科大学附属皮肤病医院(山东省皮肤病医院)山东省皮肤病性病防治研究所,济南250022

出　　处：《中国麻风皮肤病杂志》2022年第3期182-184,共3页China Journal of Leprosy and Skin Diseases

摘　　要：患者,男,41岁。躯干、双侧大腿上部散在触痛性结节、斑块54天。发病前有大腿外伤史及河水接触史。皮肤组织病理检查示:真皮深部感染性肉芽肿改变。细菌培养及菌落DNA PCR测序示偶发分枝杆菌。患者行全外显子测序未发现免疫、感染相关突变,综上诊断为偶发分枝杆菌感染性肉芽肿。给予左氧氟沙星、克拉霉素、脓肿切开、穿刺引流等,病情好转。A 41-year-old man presented with a 2-month history of scattered tender nodules,plaques in his trunk and lower limbs.Before the onset of lesions,he was injured on the lateral right thigh and swam in a river.Histopathological examination revealed a dermal infectious granuloma.Mycobacterium fortuitum was confirmed by bacteria identification and PCR.No immunological or infection-related mutation was found by whole exome sequencing.The diagnosis of infectious granuloma due to Mycobacterium fortuitum was made.The patient was treated with levofloxacin,clarithromycin,abscess incision,drainage etc.,and the condition improved obviously.

关 键 词：偶发分枝杆菌 感染性肉芽肿 全外显子测序 

分 类 号：R754[医药卫生—皮肤病学与性病学]