HIV/AIDS患者继发鸟-胞内分枝杆菌复合群感染诊疗进展  

Progress in diagnosis and treatment of Mycobacterium avium-intracellulare complex infection in HIV/AIDS patients

作　　者：裴洁[1] 谢周华[1] PEI Jie;XIE Zhou-hua(Department of Tuberculosis,Fourth People’s Hospital of Nanning,Guangxi AIDS Clinical Treatment Center(Nanning),530023,China)

机构地区：[1]南宁市第四人民医院广西艾滋病临床治疗中心(南宁)结核病科,530023

出　　处：《传染病信息》2021年第6期485-489,493,共6页Infectious Disease Information

基　　金：广西壮族自治区卫生健康委员会自筹经费科研课题(Z20200616);南宁市科学技术局重点研发计划(20193008-3)。

摘　　要：随着AIDS的全球大流行,非结核分枝杆菌(nontuberculous mycobacteria,NTM)病的发病率在许多国家有逐年上升的趋势。鸟-胞内分枝杆菌复合群(Mycobacterium avium-intracellulare complex,MAC)属于NTM,MAC是目前HIV/AIDS患者中最常见的NTM病的致病菌,感染后主要表现为播散性病变和局灶性淋巴结炎。由于MAC感染缺乏特异性的临床和影像学表现,往往容易误诊、漏诊,同时治疗上也存在疗效差、疗程长、易反复等问题。本文对HIV/AIDS患者继发MAC感染的诊疗进展作一综述。With the global pandemic of HIV/AIDS,the incidence of nontuberculous mycobacteria(NTM)disease also shows an annually increasing tendency in many countries.Mycobacterium avium-intracellulare complex(MAC)is an NTM.MAC is the most common pathogenic bacteria of NTM disease among HIV/AIDS patients at present,mainly manifested as disseminated lesion and focal lymphadenitis following infection.Due to the lack of specific clinical symptoms and imaging features,MAC infection is prone to misdiagnosis or missed diagnosis.Meanwhile,there are some problems in the treatment,such as poor therapeutic effect,long course of treatment,and relapse.This article reviews the progress of diagnosis and treatment of MAC infection in HIV/AIDS patients.

关 键 词：人类获得性免疫缺陷病毒 获得性免疫缺陷综合征 鸟-胞内分枝杆菌复合群 诊断 治疗 

分 类 号：R512.91[医药卫生—内科学]