血友病合并胃肠外科疾病20 例诊疗分析  

Diagnosis and Treatment of Hemophiliacs with Gastrointestinal Surgical Diseases in 20 Cases

作　　者：郭兴坡[1] 施皓 潘占胜[1] GUO Xing-po;SHI Hao;PAN Zhan-sheng(Department of Gastrointestinal Surgery,the First Affiliated Hospital of Soochow University,Suzhou,Jiangsu,215006,China)

机构地区：[1]苏州大学附属第一医院胃肠外科,江苏苏州215006

出　　处：《中国血液流变学杂志》2021年第3期377-379,共3页Chinese Journal of Hemorheology

摘　　要：目的探讨血友病合并胃肠外科疾病的临床特点及治疗。方法回顾性分析2012年4月—2021年1月收治的血友病合并胃肠外科疾病的病例,并对其临床特点、诊疗过程及转归进行分析。结果共有20例患者纳入,除1例未接受治疗外,其余患者在接受常规治疗联合凝血因子替代治疗后,均取得较好疗效。结论血友病合并胃肠疾病患者通过接受围手术期替代治疗进行外科手术是安全的;对APTT延长及持续出血不止患者应该警惕血友病可能;血友病诊疗过程中应重视凝血因子抑制物检测。Objective To review the characteristics and therapy of hemophiliacs with gastrointestinal surgical diseases.Methods The cases of hemophiliacs with gastrointestinal surgical diseases admitted to department of gastrointestinal surgery from April 2012 to January 2021 were collected retrospectively,and their clinical characteristics,diagnosis,treatment process and outcomes were analyzed.Results Of all the 20 individuals enrolled,19 individuals get good results after receiving conventional treatment combined with coagulation factor replacement therapy,except for 1 patient who discharged without treatment.Conclusion Gastrointestinal surgery with perioperative replacement therapy is safe for hemophiliacs.Patients with persistent bleeding and prolonged APTT should be alert to hemophilia.The detection of coagulation factor inhibitors should be emphasized for hemophiliacs.

关 键 词：血友病 胃肠疾病 凝血因子 替代治疗 

分 类 号：R656[医药卫生—外科学] R554.1[医药卫生—临床医学]