Diagnostic and surgical challenges of progressive neck and upper back painless masses in Madelung’s disease: A case report and review of literature  

作　　者：Ya-Jie Yan Shi-Qing Zhou Chun-Qiao Li Yan Ruan 

机构地区：[1]Department of Otorhinolaryngology,the First Affiliated Hospital of Guangzhou University of Chinese Medicine,Guangzhou 510405,Guangdong Province,China [2]Department of Experimental Research,State Key Laboratory of Oncology in South China,Sun Yat-sen University Cancer Center,Guangzhou 510075,Guangdong Province,China [3]Department of Otorhinolaryngology head and neck,the Second Affiliated Hospital of Guangzhou University of Chinese Medicine,Guangzhou 510120,Guangdong Province,China

出　　处：《World Journal of Clinical Cases》2022年第1期361-370,共10页世界临床病例杂志

基　　金：the National Natural Science Foundation of China,No.81974581;Basic and Applied Research Foundation of Guangdong Province,China,No.2020A1515110407;Scientific Research Fund of Guangdong Provincial Bureau of Traditional Chinese Medicine China,No.20211200.

摘　　要：BACKGROUND Madelung’s disease(MD)is a chronic alcoholism-associated metabolic syndrome characterized by symmetrical subcutaneous deposition of adipose tissue in the head,neck,shoulders,back,trunk,and nerve roots of the upper and lower limbs.It is relatively rare in Asian individuals and is prone to misdiagnosis.Herein,we report a case of a patient with MD who had undergone surgical management at our hospital,and we discuss the pathogenesis,diagnosis,and treatment of MD.CASE SUMMARY We report a case of MD in a 65-year-old man of Han descent.The patient had multiple,painless progressive masses for more than five years in the neck and more than 30 years in the upper back.Because of neck mobility limitations and progressive cosmetic deformities caused by the masses,he was admitted to our hospital.He drank approximately 500 mL of liquor per day and smoked heavily for more than 30 years.Contrast-enhanced computed tomography of the neck and chest documented abundant unencapsulated,subcutaneous fatty deposits.We prepared a staged operation plan.The patient was diagnosed with MD;he was advised to abstain from alcohol and was followed up regularly.After a 3-month follow-up,no recurrence of fat accumulation was found in the surgical areas.CONCLUSION This report presents a case of surgical treatment for MD to improve clinicians'understanding of the disease.

关 键 词：Madelung’s disease Benign symmetric lipomatosis Launois–Bensaude syndrome Multiple symmetric lipomatosis LIPECTOMY Head and neck mass Case report 

分 类 号：R589[医药卫生—内分泌]