绝经后骨质疏松症中医临床实践指南(征求意见稿)  

Clinical practice guideline for postmenopausal osteoporosis with traditional Chinese medicine

作　　者：谢雁鸣[1] 刘峘[1] 姜俊杰[1] 魏戌[2] 申浩 支英杰[1] 孙晶[4] 李晋玉[5] 包晓霞[5] 师伟[6] 章轶立 XIE Yan-ming;LIU Huan;JIANG Jun-jie;WEI Xu;SHEN Hao;ZHI Ying-jie;SUN Jing;LI Jin-yu;BAO Xiao-xia;SHI Wei;ZHANG Yi-li(Institute of Basic Research in Clinical Medicine,China Academy of Chinese Medical Sciences,Beijing 100700,China;Wangjing Hospital,Chinese Academy of Chinese Medical Sciences,Beijing 100102,China;Changxindian Community Health Service Center of Fengtai District,Beijing 100072,China;Affiliated Hospital of Liaoning University of Traditional Chinese Medicine,Shenyang 110032,China;Dongzhimen Hospital,Beijing University of Chinese Medicine,Beijing 100700,China;Affiliated Hospital of Shandong University of Traditional Chinese Medicine,Ji'nan 250355,China;Beijing University of Chinese Medicine,Beijing 100029,China)

机构地区：[1]中国中医科学院中医临床基础医学研究所,北京100700 [2]中国中医科学院望京医院,北京100102 [3]丰台区长辛店社区卫生服务中心,北京100072 [4]辽宁中医药大学附属医院,辽宁沈阳110032 [5]北京中医药大学东直门医院,北京100700 [6]山东中医药大学附属医院,山东济南250355 [7]北京中医药大学,北京100029

出　　处：《中国中药杂志》2021年第22期5992-5998,共7页China Journal of Chinese Materia Medica

基　　金：国家重点研发计划项目(2018YFC1704705);北京中医药科技发展项目(JJ2016-79);中国中医科学院自主选题项目(Z0476,Z0545)。

摘　　要：绝经后骨质疏松症(PMOP)中医临床实践指南编写组由中医骨伤专业、中医妇科专业、临床流行病学专业等多学科人员组成。通过指南注册、临床问题/结局指标的收集与遴选、证据检索与筛选、制作系统评价、证据质量评价、推荐意见形成、起草指南与同行评议等过程制订。绝经后骨质疏松症的证候分型及治疗分别是肝肾阴虚证采用六味地黄丸、左归丸治疗;肾虚血瘀证采用青娥丸治疗;脾肾阳虚证采用右归丸、金匮肾气丸治疗;肾阴阳两虚证采用二仙汤治疗;疼痛症状采用独活寄生汤治疗。常用中成药有仙灵骨葆胶囊、强骨胶囊、金天格胶囊、骨疏康胶囊、护骨胶囊、金乌骨通胶囊、骨愈灵胶囊。亦可采用针刺、艾灸治疗;八段锦、五禽戏、太极拳等运动疗法;中药药膳、健康教育、预防跌倒等进行康复及日常管理。该指南的推广应用将促进中医药防治PMOP的实施,保障患者的生活质量,为临床提供PMOP的中医药安全、有效的治疗措施,从而降低骨折并发症等风险。The editorial group of the clinical practice guideline for postmenopausal osteoporosis(PMOP)with traditional Chinese medicine(TCM)(hereinafter referred to as"guideline")is composed of experts specialized in TCM orthopedics,TCM gynecology,clinical epidemiology,etc.The guideline was formulated through registration,collection and selection of clinical issues/outcome indicators,evidence retrieval and screening,preparation of systematic reviews,evaluation of evidence quality,formation of recommendations,drafting,and peer review.The syndromes and treatment of PMOP are elaborated in detail.Specifically,Liuwei Dihuang Pills and Zuogui Pills are recommended for PMOP with Yin deficiency in the liver and kidney,Qing'e Pills for PMOP with kidney deficiency and blood stasis,Yougui Pills and Jingui Shenqi Pills for PMOP with Yang deficiency in the spleen and kidney,and Er'xian Decoction for PMOP with Yin and Yang deficiency in the kidney.In addition,Duhuo Jisheng Decoction can be used to relieve pain.The commonly used Chinese patent medicines include Xianling Gubao Capsules,Qianggu Capsules,Jintiange Capsules,Gushukang Capsules,Hugu Capsules,Jinwu Gutong Capsules,and Guyuling Capsules.Acupuncture and moxibustion are also effective approaches for PMOP.The rehabilitation and daily management were carried out by exercise therapies such as Baduanjin(eight-section brocade),Wuqinxi(five-animal exercises),and Taijiquan(Tai Chi),Chinese medicine diet,health education,and fall prevention.The promotion and application of this guideline will facilitate the implementation of TCM prevention and treatment of PMOP,ensure the quality of life of PMOP patients,provide effective and safe TCM treatment measures for PMOP,and reduce the risk of fracture complications.

关 键 词：绝经后骨质疏松症 中医临床实践指南 循证指南 

分 类 号：R259[医药卫生—中西医结合]