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作 者:赵莹莹 张丹 宋娜 王涛[3] 王卓 张少茹 于佳[4] 蔡磊[1] 陈志强[1] ZHAO Yingying;ZHANG Dan;SONG Na;WANG Tao;WANG Zhuo;ZHANG Shaoru;YU Jia;CAI Lei;CHEN Zhiqiang(Department of Radiology,General Hospital of Ningxia Medical University,Yinchuan 750004,China;Department of Radiology,Fuqing City Hospital Affiliated to Fujian Medical University,Fuqing 350300,China;Clinical Medicine School of Ningxia Medical University,Yinchuan 750004,China;Department of Genetics,School of Basic Medicine,Ningxia Medical University,Yinchuan 750004,China)
机构地区:[1]宁夏医科大学总医院放射科,银川750004 [2]福建医科大学附属福清市医院影像科,福清350300 [3]宁夏医科大学临床医学院,银川750004 [4]宁夏医科大学基础医学院遗传系,银川750004
出 处:《磁共振成像》2021年第12期24-28,共5页Chinese Journal of Magnetic Resonance Imaging
基 金:宁夏回族自治区重点研发计划项目(2019BEG03033);宁夏自然科学基金项目(2020AAC03156)。
摘 要:目的探讨高b值(1000 s/mm^(2))及超高b值(2000 s/mm^(2))的弥散加权成像(diffusion weighted imaging,DWI)及表观弥散系数(apparent diffusion coefficient,ADC)对外周带前列腺良恶性病变的诊断效能。材料与方法回顾性分析2015年1月至2016年5月在宁夏医科大学总医院放射科行前列腺常规磁共振检查及超高b值DWI成像的64例患者的临床及影像学资料;两名医师根据前列腺影像报告和数据系统第二版(Prostate Imaging Reporting and Data System Version 2.0,PI-RADS V2)并采用双盲法在T2WI和DWI上用五分制对图像进行评估;采用三维感兴趣区法逐层勾画病灶,并对ADC值行直方图分析。结果 (1)对前列腺癌灶的诊断方面,超高b值(2000 s/mm^(2))获得的DWI图像的敏感度明显高于高b值(1000 s/mm^(2))(P<0.001);(2)直方图参数ADC第10百分位数(ADC_(10))的诊断效能最高,受试者操作特征(receiver operating characteristic,ROC)曲线下面积超高b值与高b值分别为0.902 [95%CI (0.802~0.962)]和0.823 [95%CI (0.707~0.907)],但超高b值与高b值ADC值诊断效能的差异无统计学意义(P>0.05)。结论超高b值与高b值所对应的ADC值直方图对外周带前列腺癌的诊断效能相似,而在b值为2000 s/mm^(2)时,DWI图像的敏感度高于1000 s/mm^(2)。因此,超高b值DWI有助于提高对外周带前列腺癌的诊断价值。Objective:To investigate the diagnostic efficiency of diffusion weighted imaging(DWI) and apparent diffusion coefficient(ADC) maps with high b value(1000 s/mm^(2)) and ultra-high b value(2000 s/mm^(2)) for benign and malignant lesions of peripheral zone prostate.Materials and Methods:The clinical and imaging data of 64 patients who underwent conventional magnetic resonance imaging and ultra-high b-value DWI imaging of the prostate in the Department of Radiology,General Hospital of Ningxia Medical University from January 2015 to May 2016 were retrospectively analyzed.The images were evaluated by two physicians on T2WI and DWI using a five-point scale based on prostate imaging reporting and data system version 2.0(PI-RADS V2) and in a double-blind fashion;the lesions were delineated layer by layer on DWI using three-dimensional region of interest(VOI) and the histogram analysis was performed on the ADC values.Results:(1) For the diagnosis of prostate cancer,the sensitivity of DWI image obtained by ultra-high b value(2000 s/mm^(2)) was significantly higher than that of high b value(1000 s/mm^(2))(P<0.001);(2) Histogram parameter ADC_(10) had the highest diagnostic efficiency,with the areas under the receiver operating characteristic(ROC) curves of 0.902 [95% CI(0.802—0.962)] and 0.823 [95% CI(0.707—0.907)] respectively(P>0.05).Conclusions:The diagnostic performance of histogram of ADC values corresponding to ultra-high b value and high b value for peripheral zone prostate cancer is similar,while when b value is 2000 s/mm^(2),the sensitivity of DWI image is higher than 1000 s/mm^(2).Therefore,ultra-high b-value DWI can help to improve the diagnostic value of peripheral zone prostate cancer.
关 键 词:前列腺癌 磁共振成像 诊断 弥散加权成像 超高b值 直方图分析
分 类 号:R445.2[医药卫生—影像医学与核医学] R737.25[医药卫生—诊断学]
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