功能磁共振成像评估肾功能的研究进展  

Advances in functional magnetic resonance imaging for renal function assessment

作　　者：刘亚男 赵瑞峰[2] LIU Ya'nan;ZHAO Ruifeng(Shanxi Medical University,Taiyuan 030001,China;Department of Imaging,Shanxi Jincheng General Hospital,Shanxi Medical University,Jincheng 048006,China)

机构地区：[1]山西医科大学,太原030001 [2]山西医科大学附属晋城大医院影像科,晋城048006

出　　处：《磁共振成像》2021年第12期118-120,124,共4页Chinese Journal of Magnetic Resonance Imaging

摘　　要：多种疾病均可引起肾功能的异常,早期、准确评估肾功能是临床诊疗的重点。目前可用的临床生物标记物不能准确地早期发现肾功能不全、评估其严重程度和进展。随着功能磁共振(functional magnetic resonance imaging,fMRI)技术的快速发展,血氧水平依赖成像、扩散加权成像、体素内不相干运动成像、扩散张量成像和动脉自旋标记等fMRI技术可以无创地从氧合、扩散及灌注等方面评估肾功能,为肾脏疾病的早期诊断、进展及预后评估提供更多信息。本文对多种功能磁共振成像的原理及其评估肾功能方面的研究现状做一阐述。Various diseases can cause abnormal renal function.Early and accurate evaluation of renal function is the focus of clinical diagnosis and treatment.Currently available clinical biomarkers cannot accurately detect renal insufficiency early and assess its severity and progression.With the rapid development of functional magnetic resonance imaging(fMRI) technology,fMRI techniques such as blood oxygen level-dependence imaging,diffusion-weighted imaging,intravoxel incoherent motion imaging,diffusion tensor imaging,and arterial spin labeling can noninvasively assess renal function from oxygenation,diffusion and perfusion,providing more information for the early diagnosis,progression and prognosis of renal disease.In this paper,the principle of fMRI and its evaluation of renal function are described.

关 键 词：肾脏 肾功能 磁共振成像 扩散加权成像 动脉自旋标记 血氧水平依赖 

分 类 号：R445.2[医药卫生—影像医学与核医学] R692[医药卫生—诊断学]