植物病毒纳米颗粒在医学领域中的应用  

Application of plant virus nanoparticles in tumor therapy

作　　者：杜志游[1] 周昀茜 董温昕 DU Zhiyou;ZHOU Yunqian;DONG Wenxin(College of Life Sciences and Medicine,Zhejiang Sci-Tech University,Hangzhou 310018,China)

机构地区：[1]浙江理工大学生命科学与医药学院,杭州310018

出　　处：《浙江理工大学学报（自然科学版）》2022年第1期109-114,共6页Journal of Zhejiang Sci-Tech University(Natural Sciences)

基　　金：浙江省新苗人才计划项目(2019R406013)。

摘　　要：植物病毒粒子作为纳米级颗粒,具有在植物细胞内积累水平高、再生成本低、纯化工艺简单及对人体安全等优点,是一种理想的天然纳米材料。随着生物纳米技术的发展,植物病毒纳米颗粒在医学领域展现出越来越大的应用潜力,本文围绕靶向传递药物、分子成像和疫苗制备综述了植物病毒纳米颗粒在医学领域的研究进展和应用。Plant viruses, as nanoscale particles, are ideal natural nanomaterials with the advantages of high accumulation level in plant cells, low regeneration cost, simple purification process and safety to human body. With the development of biological nanotechnology, plant virus nanoparticles have shown increasing application potential in the medical field. In this paper, we will review the research progress and application of plant virus nanoparticles in the medical field from three aspects: targeted drug delivery, molecular imaging and vaccine preparation.

关 键 词：植物病毒 纳米颗粒 成像 疫苗 药物传递 

分 类 号：S132.41[农业科学—农业基础科学]