4,4’-二硝基二苯硫醚的研究进展  

Research progress of 4,4’-dinitrodiphenylsulf ide

作　　者：李煜 王国胜 LI Yu;WANG Guo-sheng(College of Chemical Technology,Shenyang University of Chemical Technology,Shenyang 110142,China)

机构地区：[1]沈阳化工大学化学工程学院,辽宁沈阳110142

出　　处：《化工管理》2022年第1期60-63,99,共5页Chemical Engineering Management

摘　　要：近年来,4,4’-二硝基二苯硫醚作为有机合成中间体,在农药、医药等领域被广泛应用。综述了近几年国内外研究4,4’-二硝基二苯硫醚化合物的进展,重点介绍了其合成方法,分析了这些合成方法所具有的优势及其潜在的不足,根据几种合成方法探讨出目前最适宜工业化生产的形式。经过比较,4-硝基氯苯与硫化钠在十六烷基三甲基溴化铵催化作用下的反应因其原料易得、操作简单为最佳的工艺制备方法。并且将开发廉价的催化剂用于工业化生产作为未来的研究重点和发展方向。In recent years,4,4’-dinitrodiphenylsulf ide,as an organic synthesis intermediate,has been widely used in the f ields of pesticide,medicine and so on.The progress of research on 4,4’-dinitrodiphenylsulf ide compounds at home and abroad in recent years is reviewed.The synthesis methods of 4,4’-dinitrodiphenyl sulf ide are mainly introduced.The advantages and potential disadvantages of these synthesis methods are analyzed.According to several synthesis methods,the most suitable form of industrial production is discussed.By comparison,the reaction of p-chloronitrobenzene and Sodium Sulf ide Catalyzed by cetyltrimethylammo-nium bromide is the best process because of its easy to obtain raw materials and simple operation.And the development of cheap catalysts for industrial production will be the future research focus and development direction.

关 键 词：4 4’-二硝基二苯硫醚 硫化钠 取代 合成工艺 中间体 

分 类 号：O625.72[理学—有机化学]