腰椎间盘突出症患者血常规与凝血功能变化及意义  

Changes and significance of blood routine and coagulation function in patients with lumbar disc herniation

作　　者：钟学仁[1] 包拥政[1] 吴强[1] 席新华[1] 胡孔和[1] 熊英辉[1] 卢林俊[1] 胡永玉 骆影超 ZHONG Xueren;BAO Yongzheng;WU Qiang;XI Xinhua;HU Konghe;XIONG Yinghui;LU Linjun;HU Yongyu;LUO Yingchao(Department of Spinal Surgery,North Guangdong People's Hospital,Shaoguan,Guangdong,China,512026)

机构地区：[1]广东省粤北人民医院脊柱外科,广东韶关512026

出　　处：《分子诊断与治疗杂志》2021年第12期2069-2072,共4页Journal of Molecular Diagnostics and Therapy

基　　金：韶关市卫生计生科研计划项目(Y19019)。

摘　　要：目的检测腰椎间盘突出症(LDH)患者血常规与凝血功能相关数据变化,分析其意义。方法选取2019年1月到2020年12月广东省粤北人民医院脊柱外科收治123例LDH患者作为观察组,选41例同期体检健康者作为对照组。比较两组血常规指标寄凝血功能指标。结果观察组RBC、Hb水平均显著低于对照组,MO水平高于对照组,差异有统计学意义(P<0.05);观察组PLT水平高于对照组,但差异并无统计学意义(P>0.05);观察组APTT、PT、Fib水平显著低于对照组,差异具有统计学意义(P<0.05);Fib、PT、APTT、Hb曲线下面积AUC均>0.7,有一定诊断效能(P<0.05)。结论检测机体血常规及凝血功能水平,对于LDH诊断治疗有重要指导意义。Objective to detect the changes of blood routine and coagulation function in patients with lumbar disc herniation(LDH)and analyze its significance. Methods 123 patients with LDH treated in our hospital from January 2019 to December 2020 were selected as the observation group,and 41 healthy people in the same period were selected as the control group. Blood routine indexes and coagulation function indexes were compared between the two groups. Results the levels of RBC and Hb in the observation group were significantly lower than those in the control group,and the level of Mo was higher than that in the control group(P<0.05);The PLT level in the observation group was higher than that in the control group,but the difference was not statistically significant(P>0.05);The levels of APTT,Pt and Fib in the observation group were significantly lower than those in the control group(P<0.05);AUC under FIB,Pt,APTT and Hb curves were >0.7,which had certain diagnostic efficiency. Conclusion the detection of blood routine and coagulation function level has important guiding significance for the diagnosis and treatment of LDH.

关 键 词：腰椎间盘突出 血常规 凝血功能 诊断标准 临床意义 

分 类 号：R681.53[医药卫生—骨科学]