瑶药皂布叶质量标准研究  

Study on Quality Standard for Rhamnus napelensis

作　　者：张婷[1] 刘华东[1] 刘安韬[1] 卢月妹 无 ZHANG Ting;LIU Huadong;LIU Antao;LU Yuemei(Guangxi Medical College,Nanning 530023,China;Youjiang Medical University for Nationalities,Baise 533000,China)

机构地区：[1]广西卫生职业技术学院,广西南宁530023 [2]右江民族医学院,广西百色533000

出　　处：《中国民族民间医药》2021年第24期41-44,共4页Chinese Journal of Ethnomedicine and Ethnopharmacy

基　　金：广西壮族自治药品监督管理局2018年食品药品监管科研项目(GXZC2018-C3-20716-XYGC);2018年中药特色技术传承人才培训项目(T20184828005)。

摘　　要：目的:建立皂布叶Rhamnus napelensis(Wall.)Laws药材的质量标准。方法:以广西采集的12批皂布叶药材为研究对象,采用2020版《中国药典》(四部)相关方法检查其水分、总灰分和浸出物含量;采用紫外-可见分光光度法,醋酸镁-甲醇显色测定总蒽醌含量。结果:12批药材水分和总灰分分别不高于13%和6%,水溶性浸出物和醇溶性浸出物不低于15%和12%。总蒽醌在0.002074-0.01037 mg范围内线性关系良好(R 2=0.9962)。含量测定结果显示,该药材总蒽醌含量(以1,8-二羟基蒽醌计)不得少于20.0 mg/g。结论:建立的项目考察了皂布叶的各项质量指标,能有效评价药材的质量。Objective To establish the quality standard for Rhamnus napelensis.Methods Twelve batches of Rhamnus napelensis collected in Guangxi region.The samples were examined by moisture measuring,ash determination and extract mensuration method according to Chinese Pharmacopoeia(2020 edition).UV spectrophotometry was developed to determinate the total anthraquinone.Results In twelve batches of Rhamnus napelensis,the water content and the average content of total ash is less than 13%and 6.0%,respectively;the content of water and alcohol-soluble extract were above 15%and 12%,respectively.The calibration curves of the total anthraquinone had good linear relationship in the ranges of 0.002074~0.01037 mg(R 2=0.9962).Total anthraquinone is more than 20.0 mg/g.Conclusion Identification methods were stable and reliable,Established quality standard can be used for comprehensive quality control of Rhamnus napelensis.

关 键 词：皂布叶 总蒽醌 质量标准 

分 类 号：R284.1[医药卫生—中药学]