丙泊酚复合瑞芬太尼全凭静脉麻醉在脑动脉瘤介入治疗中的应用效果  

Application effect of total intravenous anesthesia with propofol and remifentanil in interventional treatment of cerebral aneurysms

作　　者：朱祥 ZHU Xiang(Nanjing Third Hospital,Nanjing 210009,China)

机构地区：[1]南京市第三医院,210009

出　　处：《中国实用医药》2021年第36期144-146,共3页China Practical Medicine

摘　　要：目的观察丙泊酚复合瑞芬太尼全凭静脉麻醉在脑动脉瘤介入治疗中的应用效果。方法80例行介入治疗的脑动脉瘤患者,通过随机抽取双色球分组方式分为对照组及研究组,各40例。对照组采取丙泊酚复合芬太尼全凭静脉麻醉,研究组采取丙泊酚复合瑞芬太尼全凭静脉麻醉。对比两组患者不同时间点的平均动脉压及心率,苏醒间隔时长与拔管间隔时长,不良反应发生情况。结果麻醉诱导前,两组的平均动脉压及心率对比,差异无统计学意义(P>0.05);气管插管后10 min、股动脉管留置后1 min、手术期间、气管导管拔除后3 min,研究组的平均动脉压及心率均低于对照组,差异具有统计学意义(P<0.05)。研究组的苏醒间隔时长为(9.59±4.19)min、拔管间隔时长为(15.88±6.11)min,均短于对照组的(19.85±6.42)、(28.86±10.21)min,差异具有统计学意义(P<0.05)。研究组不良反应发生率为0,低于对照组的10.00%,差异具有统计学意义(P<0.05)。结论在脑动脉瘤患者介入治疗中采取丙泊酚复合瑞芬太尼全凭静脉麻醉,是一种安全有效的麻醉方式。Objective To observe the application effect of total intravenous anesthesia with propofol and remifentanil in interventional treatment of cerebral aneurysms.Methods A total of 80 cases of cerebral aneurysm patients undergoing interventional treatment were divided into the control group and the research group by two-color ball method,with 40 cases in each group.The control group took propofol combined with fentanyl for total intravenous anesthesia,and the research group took propofol combined with remifentanil for total intravenous anesthesia.Both groups were compared in terms of mean arterial pressure and heart rate at different time points,recovery interval,extubation interval,and occurrence of adverse reactions.Results Before induction of anesthesia,the differences in mean arterial pressure and heart rate between the two groups were not statistically significant(P>0.05).The mean arterial pressure and heart rate of the research group were lower than those of the control group 10 min after tracheal intubation,1 min after femoral artery tube placement,during surgery,and 3 min after tracheal tube removal,and the differences were statistically significant(P<0.05).The recovery interval and extubation interval of the research group were(9.59±4.19)and(15.88±6.11)min,which were shorter than(19.85±6.42)and(28.86±10.21)min of the control group,and the differences were statistically significant(P<0.05).The incidence of adverse reactions in the research group was 0,which was lower than 10.00%in the control group,and the difference was statistically significant(P<0.05).Conclusion Total intravenous anesthesia with propofol and remifentanil is a safe and effective method for patients with cerebral aneurysm undergoing interventional therapy.

关 键 词：丙泊酚 瑞芬太尼 全凭静脉麻醉 脑动脉瘤 介入治疗 

分 类 号：R614[医药卫生—麻醉学]