微波消解-电感耦合等离子体质谱法测定启脾丸中重金属及有害元素含量  

Determination of Heavy Metals and Harmful Elements in Qipi Pill by Miccorowave Digestion-ICP-MS

作　　者：刘嘉乐 谢秋红[2] 李正刚 邵大志[1] 王丹彧 马彧[1] LIU Jiale;XIE Qiuhong;LI Zhenggang;SHAO Dazhi;WANG Danyu;MA Yu(Siping Institute for Food and Drug Control,Siping 136000,China;Siping Central People’s Hospital,Siping 136000,China)

机构地区：[1]四平市食品药品检验所,吉林四平136000 [2]四平市中心人民医院,吉林四平136000

出　　处：《现代食品》2021年第24期181-184,共4页Modern Food

基　　金：吉林省科技厅项目-重点研发-医药健康领域(20210204151YY)。

摘　　要：本文建立了启脾丸中铅、砷、汞、镉、铜5种重金属及有害元素含量的测定方法。样品经微波消解后,采用电感耦合等离子体质谱(ICP-MS)测定5种金属元素的含量,以锗(^(72)Ge)、铟(^(115)In)、铋(^(209)Bi)混合溶液作为内标。铅、砷、汞、镉、铜5种待测元素的线性关系良好(r≥0.9994),回收率在91.6%~105.8%(RSD≤7.1%),方法检测限在0.019~0.036 mg·kg^(-1)。5批样品均不同程度检出了铅、砷、汞、镉、铜,但均在安全限度之内。该方法准确,灵敏度高,启脾丸产品质量安全可靠。This paper established a method to determine the content of lead,arsenic,mercury,cadmium,copper and harmful elements in Qipi pills.After the sample was digested by microwave,the content of 5 metal elements was determined by inductively coupled plasma mass spectrometry(ICP-MS),and a mixed solution of ^(72)Ge,^(115)In,and ^(209)Bi was used as an internal standard.Lead,arsenic,mercury,cadmium,and copper have a good linear relationship(r≥0.9994),the recovery rate is 91.6%~105.8%(RSD≤7.1%),and the method detection limit is 0.019~0.036 mg·kg^(-1).Lead,arsenic,mercury,cadmium,and copper were detected in the 5 batches of samples to varying degrees,but they were all within the safety limits.The method is accurate and sensitive,and the quality of Qipi pills is safe and reliable.

关 键 词：启脾丸 重金属及有害元素 微波消解 电感耦合等离子体质谱 

分 类 号：O657.63[理学—分析化学]