肉用绵羊黄脂病的诊断及病理学变化  

Diagnosis and Pathology of Yellow Fat Disease in Sheep

作　　者：张凯歌 王梦瑶 张冰雨 杨玉荣[1] 姜义宝[1] ZHANG Kai-ge;WANG Meng-yao;ZHANG Bing-yu;YANG Yu-rong;JIANG Yi-bao(College of Animal Science,Henan Agricultural University,Zhengzhou 450000,China)

机构地区：[1]河南农业大学动物科技学院,河南郑州450000

出　　处：《中国兽医杂志》2021年第10期30-33,共4页Chinese Journal of Veterinary Medicine

基　　金：河南省科技厅自然科学基金(202300410214)。

摘　　要：本试验应用石蜡切片、H.E.染色技术和元素分析法对河南和山东某肉羊养殖场的黄脂病病例进行了病因学和病理变化方面的分析和研究。结果显示:绵羊血清、肝脏、肾脏以及饲料的铜元素含量检测结果远高于参考水平;病理学特征为黏膜、脂肪黄染,贫血,胆囊极度充盈,肝脏肿大、黄染,肾脏肿大,呈均匀黑色;病理组织学变化主要是急性坏死性肝炎和急性肾小管坏死炎,伴有大量的胆色素、血红蛋白的沉积。本试验结果表明该集约化养殖场绵羊黄脂病的病因是慢性铜中毒。Cases of yellow fat disease sheep were collected from intensive farms in Henan province and Shandong province.Etiology and pathology were explored by paraffin sections,H.E.staining and elemental analysis.The results showed that copper content in serum,liver,kidney and feed were higher than reference level.Pathological characters included yellow staining of mucosa and fat,anemia,enlarged gallbladder and filled bile,yellow and enlarged liver,enlarged kidney with uniform dark color.Acute necrotizing hepatitis and acute kidney tubular necrosis,accompanied by a large amount of cholochrome and hemoglobin deposition were observed under microscope.Thus chronic copper toxicosis appeared to be the cause of yellow fat disease in these intensivly farmed sheep.

关 键 词：绵羊 黄脂病 铜中毒 病理组织学 

分 类 号：S831.5[农业科学—畜牧学]