母亲孕期铁营养状况对6~12月龄婴儿缺铁性贫血的影响  

Effect of iron nutritional status during pregnancy on iron deficiency anemia in infants aged 6-12 months

作　　者：陈承娣 林媛媛 章依文[1] CHEN Chengdi;LIN Yuanyuan;ZHANG Yiwen(Department of Developmental and Behavioral Pediatrics, Shanghai Children's Medical Center, Shanghai Jiao Tong University School of Medicine, Shanghai 200127, China)

机构地区：[1]上海交通大学医学院附属上海儿童医学中心发育行为儿科,中国上海200127

出　　处：《教育生物学杂志》2021年第6期496-500,共5页Journal of Bio-education

摘　　要：目的通过对6~12月龄婴儿缺铁性贫血的筛查和影响因素分析,探讨母亲孕期铁营养状况对婴儿缺铁性贫血的影响,为婴儿贫血的防治提供科学依据。方法收集2019年1月—2020年6月在上海唯儿诺诊所接受体检的6~12月龄婴儿的资料,对常规儿童保健体检内容(生长发育指标、血常规、铁代谢检查资料及问卷调查资料等)进行回顾性分析。结果共收集342名6~12月龄婴儿的资料,其中缺铁性贫血婴儿51例,占比14.91%。母亲孕期贫血占比26.90%,其中孕早期、中期、晚期贫血分别占比19.57%、55.43%、23.91%。母亲孕期补铁者占比34.80%。分组分析结果显示:缺铁性贫血组与非缺铁性贫血组比较,母亲孕期的铁营养状况(孕期贫血、孕期铁剂补充情况、孕期贫血恢复情况)、母亲体质量指数(body mass index,BMI)和婴儿出生体质量的差异均有统计学意义(均P<0.05)。控制母亲BMI和婴儿出生体质量后,Logistic回归分析结果显示母亲孕期贫血仍是婴儿缺铁性贫血的危险因素(OR>1,P<0.05)。结论母亲孕期贫血是6~12月龄婴儿缺铁性贫血的主要危险因素。为了避免婴儿发生缺铁性贫血,预防母亲孕期贫血是关键。Objective To explore the iron nutritional status during pregnancy and its influence on iron deficiency anemia(IDA)of infants by screening and analyzing the influencing factors of IDA of infants aged 6-12 months,so as to provide scientific basis for the prevention and treatment of infant anemia.Methods The infants aged 6-12 months who underwent physical examination in Shanghai Wellem Clinic from January 2019 to June 2020 were enrolled.And the data of routine health examination(physical examination,blood routine test,iron metabolism examination,and questionnaire survey)were analyzed retrospectively.Results Among 342 infants aged 6-12 months,51 infants with IDA were detected,accounting for 14.91%.Maternal anemia during pregnancy was 26.90%,including 19.57%in early pregnancy,55.43%in middle pregnancy,and 23.91%in late pregnancy.Maternal iron supplementation during pregnancy accounted for 34.80%.The results of grouping analysis showed that between IDA group and non-IDA group,there were significant differences in maternal iron nutrition status(anemia during pregnancy,iron supplement during pregnancy,and recovery of anemia during pregnancy),maternal body mass index(BMI),and infant birth weight(P<0.05).After adjusting maternal BMI and infant birth weight,Logistic regression analysis showed that maternal anemia during pregnancy was still a risk factor for infant with IDA(OR>1,P<0.05).Conclusion Anemia during pregnancy is the main risk factor of IDA in infants aged 6-12 months.Prevention of anemia during pregnancy is key to prevent IDA in infants.

关 键 词：缺铁性贫血 孕期 铁营养 婴儿 

分 类 号：R72[医药卫生—儿科]