Papillon-Lefèvre Syndrome: A Case Report  

作　　者：Yu-Lei Zhao Zhao Feng Bin Hu Liu-Qing Chen 

机构地区：[1]Department of Dermatology,The Third Hospital of Soochow University,Changzhou,Jiangsu,213003,China [2]Department of Dermatology,Wuhan No.1 Hospital,Tongji Medical College,Huazhong University of Science and Technology,Wuhan,Hubei 430022,China

出　　处：《International Journal of Dermatology and Venereology》2021年第2期97-99,共3页国际皮肤性病学杂志（英文）

摘　　要：Introduction:Papillon-Lefèvre syndrome(PLS)is an autosomal recessive disorder characterized by a diffuse palmoplantar hyperkeratosis and early periodontal destruction.Only a few PLS cases are reported by dermatological clinicians due to its rarity.Case presentation:The patient had also experienced recurrent episodes of swollen gums with premature loss of teeth.He is treated with multidisciplinary approaches.On follow-up,he continued to have recurrent gingival inflammation.Discussion:The etiopathogenesis of PLS is obscure and its management presents a special challenge,which call for in-depth studies that will reveal the complex interactions of genetic,immunologic,and microbiological factors involved in pathogenesis of PLS.Conclusion:PLS is a very rare genodermatosis with characterized palmoplantar hyperkeratosis.Dermatological clinicians should be aware of this rare clinical entity to promote its early diagnosis.

关 键 词：Papillon-Lefvre syndrome Palmar-plantar hyperkeratosis Case report 

分 类 号：R596.1[医药卫生—内科学]