富血小板血浆与曲安奈德对肱骨外上髁炎的疗效比较  

Comparison of Therapeutic Effects of Platelet-Rich Plasma and Triamcinolone Acetonide on Lateral Epicondylitis of Humerus

作　　者：陈锦鸿 李智 吴文涛 王文斐 娄朝晖[1] CHEN Jinhong;LI Zhi;WU Wentao;WANG Wenfei;LOU Zhaohui(The Fifth Department of Orthopedic,the First Affiliated Hospital of Zhengzhou University,Zhengzhou 450000,China)

机构地区：[1]郑州大学第一附属医院骨五科,河南郑州450000

出　　处：《河南医学研究》2022年第1期71-74,共4页Henan Medical Research

基　　金：河南省医学科技攻关计划省部共建项目(SBGJ2018030)。

摘　　要：目的比较富血小板血浆(PRP)与曲安奈德对肱骨外上髁炎的疗效。方法选取2020年1—7月于郑州大学第一附属医院骨科门诊接受诊疗的40例肱骨外上髁炎患者。严格随机分为对照组(20例)和PRP组(20例)。对照组患者接受曲安奈德注射治疗,PRP组患者接受PRP注射治疗。比较两组预治疗和治疗后1、6个月及1 a的视觉模拟量表(VAS)、前臂-肩部-手功能障碍快速问卷(QDASH)评分及Mayo肘关节功能评分(MEPS)。结果治疗后1个月,PRP组VAS评分、QDASH评分高于对照组(P<0.05);治疗后6个月及1 a,PRP组VAS评分、QDASH评分低于对照组(P<0.05)。随着治疗时间的延长,PRP组VAS评分、QDASH评分呈现逐渐下降趋势(P<0.05);对照组VAS评分、QDASH评分在治疗后1个月达到最低,之后呈现上升趋势(P<0.05)。治疗后1个月,PRP组MEPS评分低于对照组(P<0.05);治疗后6个月及1 a,PRP组MEPS评分高于对照组(P<0.05)。随着治疗时间的延长,PRP组MEPS评分呈现逐渐上升趋势(P<0.05);对照组MEPS评分于治疗后1个月达到最高,之后呈现下降趋势(P<0.05)。结论PRP注射与曲安奈德均可用于治疗肱骨外上髁炎,但曲安奈德注射的短期效果好,远期效果欠佳,而PRP注射后疼痛及功能逐步改善,远期效果更可靠。Objective To compare the therapeutic effects of platelet-rich plasma(PRP)and triamcinolone acetonide on lateral epicondylitis of humerus.Methods Forty patients with lateral epicondylitis of humerus treated in the Orthopaedic Clinic of the First Affiliated Hospital of Zhengzhou University from January to July 2020 were selected.They were randomly divided into control group(20 cases)and PRP group(20 cases).The patients in control group were treated with triamcinolone acetonide injection.The patients in PRP group received PRP injection.Visual analogue scale(VAS),quick disabilities of the arm,shoulder and hand(QDASH)and Mayo elbow-performance score(MEPS)were compared between the two groups at pretreatment,1 month,6 months and 1 year after treatment.Results One month after treatment,the scores of VAS and QDASH in PRP group were higher than those in control group(P<0.05).After 6 months and 1 year of treatment,the scores of VAS and QDASH in PRP group were lower than those in control group(P<0.05).With the prolongation of treatment time,the scores of VAS and QDASH in PRP group showed a decreasing trend(P<0.05).The scores of VAS and QDASH in control group reached the lowest one month after treatment,and then showed an upward trend(P<0.05).One month after treatment,MEPS score in PRP group was lower than that in control group(P<0.05).After 6 months and 1 year of treatment,MEPS score of PRP group was higher than that in control group(P<0.05).With the prolongation of treatment time,MEPS score in PRP group showed a gradual upward trend(P<0.05).MEPS score in control group reached the highest level one month after treatment,and then showed a downward trend(P<0.05).Conclusion Both PRP injection and triamcinolone acetonide can be used to treat lateral epicondylitis of humerus,but triamcinolone acetonide injection has good short-term effect and poor long-term effect,while PRP injection gradually improves pain and function and the long-term effect is more reliable.

关 键 词：肱骨外上髁炎 富血小板血浆 皮质类固醇 曲安奈德 

分 类 号：R681.7[医药卫生—骨科学]