德宏傣族景颇族自治州跨境婚姻人群的HCV感染的流行病学调查  

Prevalence and correlates of HCV infection among cross-border couples in Dehong Prefecture

作　　者：杨跃诚 李自慧 李林 叶润华 杜本丽 汪沉波 何志群[5] 聂永英 李维美[7] 王继宝 姚仕堂 丁盈盈[2] 何纳[2] 段松 YANG Yue-cheng;LI Zi-hui;LI Lin;YE Run-hua;DU Ben-li;WANG Chen-bo;HE Zhi-qun;NIE Yong-ying;LI Wei-mei;WANG Ji-bao;YAO Shi-tang;DING Ying-ying;HE Na;DUAN Song(Department of Sexual and AIDS Prevention,Dehong Dai and Jinpo Autonomous Prefecture Center for Dis-ease Control and Prevention,Mangshi 678400,China;Department of Epidemiology,Key Laboratory of Public Health Safety of Ministry of Education,School of Public Health,Fudan University,Shanghai 200032,China;Department of Sexual and AIDS Prevention,Mang City Center for Disease Control and Prevention,Mangshi 678400,China;Department of Sexual and AIDS Prevention,Ruili Center for Disease Control and Prevention,Ruili 678600,China;Department of Sexual and AIDS Prevention,Long-chuan Center for Disease Control and Prevention,Longchuan 678700,China;Department of Sexual and AIDS Prevention,Yingjiang Center for Disease Control and Prevention,Yingjiang 679300,China;Department of Sexual and AIDS Prevention,Lianghe Center for Disease Control and Prevention,Lianghe 679200,China)

机构地区：[1]云南德宏傣族景颇族自治州疾病预防控制中心性病艾滋病防制科,芒市678400 [2]复旦大学公共卫生学院流行病学教研室公共卫生安全教育部重点实验室,上海200032 [3]芒市疾病预防控制中心性病艾滋病防制科,芒市678400 [4]瑞丽市疾病预防控制中心性病艾滋病防制科,瑞丽678600 [5]陇川县疾病预防控制中心性病艾滋病防制科,陇川678700 [6]盈江县疾病预防控制中心性病艾滋病防制科,盈江679300 [7]梁河县疾病预防控制中心性病艾滋病防制科,梁河679200

出　　处：《中华疾病控制杂志》2021年第12期1374-1379,1386,共7页Chinese Journal of Disease Control & Prevention

基　　金：国家科技重大专项(2018ZX10715006-001,2018ZX10721102-004);国家自然科学基金(81773485)。

摘　　要：目的了解德宏傣族景颇族自治州(简称德宏州)跨境婚姻人群HCV的感染状况以及相关因素。方法横断面研究。2017年5月1日―2018年6月30日通过问卷调查收集研究对象的基本信息,并抽5 ml血72 h内检测HCV抗体。结果共调查35188人,其中31948人接受了HCV抗体检测,阳性770人,阳性率2.41%,其中中国籍调查对象HCV感染率为3.42%(518/17150),缅籍调查对象的感染率为1.50%(252/16798)。男性HCV感染率为3.64%,高于女性的1.33%。景颇族男性的感染率高于其他民族,为7.08%。男性静脉注射吸毒者HCV感染率高达85.23%。有过非婚非商业性行为的女性HCV感染率为29.94%。多因素Logistic回归分析模型结果显示,跨境婚姻人群男性感染HCV的危险因素为:年龄≥30岁、少数民族、吸毒史、非婚性行为史以及HIV感染,女性感染HCV的危险因素为:年龄≥30岁、景颇族、吸毒史、非婚非商业性行为史和HIV感染。结论德宏州跨境婚姻人群HCV感染率高于一般人群,需要进一步加强吸毒人群HCV检测与丙型肝炎知识宣传和防治工作。Objective To investigate the HCV prevalence and associated factors among cross-border couples in Dehong Prefecture.Methods Information was collected through face-to-face questionnaire survey in this cross-sectional study.The contents of the questionnaire included basic information and 5 ml venous blood of the respondents was collected and sent to HIV confirmation laboratory within 72 hours.Results Among 31 948 participants,HCV prevalence was 2.41% overall,but the prevalence was higher among Chinese natives than foreign spouses [3.42%(518/17 150) versus 1.50%(252/16 798)].The HCV prevalence was higher in male spouses than female spouses(3.64% versus 1.33%).Prevalence of HCV infection was up to 85.23% among male spouses who were injection drug users,and up to 29.94% among female spouses who had ever have extramarital noncommercial sexual behaviors.In multivariable Logistic regression model analysis,aged ≥30 years,ethnic minorities,history of drug use,extramarital sex,and HIV infection were significantly associated with HCV infection among male spouses,whereas aged ≥30 years,Jingpo ethnic minority,drug user,noncommercial extramarital sex and HIV infection were significantly associated with HCV infection among female spouses.Conclusion The epidemic of HCV among cross-border couples in Dehong is severe,requiring more health education about HCV prevention.

关 键 词：跨境婚姻 HCV感染 感染率 危险因素 

分 类 号：R512.63[医药卫生—内科学] R181[医药卫生—临床医学]