安徽省强制戒毒人群HIV、HCV和梅毒感染状况及影响因素分析  

Prevalence and influencing factors of HIV,HCV and syphilis among drug addicts in compulsory detoxification center of Anhui Province

作　　者：姚晖[1] 张思晨 冯金保[1] 陈超杰[1] 王海[3] 类延花[3] 范引光[2] YAO Hui;ZHANG Si-chen;FENG Jin-bao;CHEN Chao-jie;WANG Hai;LEI Yan-hua;FAN Yin-guang(STD and AIDS Prevention Department,Hefei Center for Disease Control and Prevention,Hefei 230032,China;Department of Epidemiology and Biostatistics,School of Public Health,Anhui Medical University,Inflammation and Immune Mediated Diseases Laboratory of Anhui Province,Hefei 230032,China;Physical and Chemical Laboratory,Hefei Center for Disease Control and Prevention,Hefei 230032,China)

机构地区：[1]合肥市疾病预防控制中心艾滋病性病防治科,合肥230061 [2]安徽医科大学公共卫生学院流行病与卫生统计学系炎症免疫性疾病安徽省实验室,合肥230061 [3]合肥市疾病预防控制中心理化检验科,合肥230061

出　　处：《中华疾病控制杂志》2021年第12期1403-1408,共6页Chinese Journal of Disease Control & Prevention

基　　金：2020年中国疾病预防控制中心艾滋病防治现场技术支持项目(K2020043);安徽省教育厅自然科学重点项目(900206)。

摘　　要：目的了解安徽省强制戒毒人群行为特征及HIV、HCV和梅毒感染状况,并探究其影响因素。方法以2018年7月1日―2020年6月30日新进入安徽省滨湖强制隔离戒毒所的强制戒毒人员作为调查对象,收集调查对象人口学和行为学信息,采集血液进行相关抗体检测,并进行单因素χ^(2)检验和多因素Logistic回归分析模型分析探究感染的影响因素。结果950名戒毒人员以男性为主,平均年龄(34.98±8.54)岁,吸食新型毒品者占84.5%(803/950)。HIV、HCV和梅毒抗体阳性率分别为1.2%、10.0%和9.2%。多因素Logistic回归分析结果表示,女性(OR=3.84,95%CI=2.35~6.27)、HIV抗体阳性(OR=6.19,95%CI=1.42~26.96)是梅毒感染的影响因素,最近1年接受过同伴教育(OR=0.44,95%CI=0.23~0.87)是梅毒感染的保护因素;而女性(OR=2.05,95%CI=1.08~3.89)、年龄≥50岁(OR=6.77,95%CI=1.35~33.95)、注射吸毒(OR=51.84,95%CI=27.65~97.19)是HCV感染的影响因素。结论安徽省强制戒毒人群以新型毒品吸食者为主,需加强对新型毒品的管制,同时针对女性、高龄组和有注射行为吸毒人群制定有效干预措施。Objective To understand the behavioral characteristics and the prevalence rates of HIV,HCV and syphilis,and to explore the influencing factors among drug addicts in compulsory detoxification center of Anhui Province.Methods Drug addicts who newly entered the Binhu compulsory detoxification center in Anhui Province from July 1,2018 to June 30,2020 were taken as the survey subjects.Demographic and behavioral information of the survey subjects were collected,and blood was collected for relevant antibody testing.Univariate Chi-Square test and multivariate Logistic regression analysis were performed to explore the influencing factors of infection.Results A total of 950 drug addicts were investigated,mainly male,with an average age of(34.98±8.54)years old.Among them,84.5%(803/950)were new drug users.The positive rate of HIV,HCV and syphilis antibodies was 1.2%,10.0%and 9.2%,respectively.Multivariate Logistic regression analyses showed that female(OR=3.84,95%CI=2.35-6.27)and HIV antibody positive(OR=6.19,95%CI=1.42-26.96)were influencing factors for syphilis infection,and peer education(OR=0.44,95%CI=0.23-0.87)is a protective factor for syphilis infection.Female(OR=2.05,95%CI=1.08-3.89),older age(OR=6.77,95%CI=1.35-33.95)and injecting drug use(OR=51.84,95%CI=27.65-97.19)were influencing factors for HCV infection.Conclusion The drug addicts in compulsory detoxification center of Anhui province are mainly new drug users.It is necessary to strengthen the control of new drugs.At the same time,effective intervention measures should be developed for women,the elderly group,and injecting drug addicts.

关 键 词：吸毒人群 HIV 梅毒 HCV 影响因素 

分 类 号：R183[医药卫生—流行病学]